---
title: Can dermatitis herpetiformis get worse before menstruation? | Niyora
description: Yes. One woman with this blistering skin condition had worsening rashes 5 days before her period through the end of menstruation, and needed to increase her m
url: https://niyora.com/research/papers/a-case-of-dermatitis-herpetiformis-with-premenstrual-exacerbation-2024/
---

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- Can dermatitis herpetiformis get worse before menstruation?

Case report, 2024

# Can dermatitis herpetiformis get worse before menstruation?

Yes. One woman with this blistering skin condition had worsening rashes 5 days before her period through the end of menstruation, and needed to increase her medication during this time.

 Early or limited evidence

29-year-old woman with dermatitis herpetiformis

## What they did

Doctors described one 29-year-old woman with a blistering skin condition on her face and upper body.

## What they found

Her rash got worse 5 days before menstruation and continued through menstruation. During this time, she needed to increase her medication from 25 mg/day to 50 mg/day to keep the rash controlled.

## What it means for you

This skin condition may get worse before menstruation, and doctors may need to adjust treatment dose during the menstrual cycle. The main limit is that this is one woman's experience and we don't know if all women with this condition experience this.

29

age

25

starting dose (mg/day)

5

days before menstruation when worsening started

## About the study

Original title A Case of Dermatitis Herpetiformis with Premenstrual Exacerbation Authors A. Matsuda, Hitoshi TSUCHIHASHI, Norito Ishii et al. Journal The Nishinihon Journal of Dermatology Year 2024 Study design Case report What was tested Dapsone Open access Yes Read the paper [doi.org/10.2336/nishinihonhifu.86.130](https://doi.org/10.2336/nishinihonhifu.86.130)

## Topics

[Premenstrual exacerbation (PME)](https://niyora.com/research/topics/condition-pme/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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