---
title: Can mood and psychotic symptoms happen before the period in women with PCOS?
description: Yes. One young woman with PCOS experienced three episodes of mixed mood and psychotic symptoms before her period. This is very rare.
url: https://niyora.com/research/papers/a-case-of-repeated-mixed-mood-episodes-with-psychotic-symptoms-associated-with-2018/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Can mood and psychotic symptoms happen before the period in women with PCOS?

Case report, 2018

# Can mood and psychotic symptoms happen before the period in women with PCOS?

Yes. One young woman with PCOS experienced three episodes of mixed mood and psychotic symptoms before her period. This is very rare.

 Early or limited evidence

One young woman with polycystic ovarian syndrome

## What they did

Described one case of a young woman with polycystic ovarian syndrome, a condition that affects hormone levels, who had mood and psychotic episodes linked to her menstrual cycle.

## What they found

She experienced three episodes. Each involved mixed mood symptoms (depression and mania together) plus psychotic symptoms (hearing or seeing things that are not real) that appeared before her period.

## What it means for you

Women with PCOS can occasionally have severe premenstrual mood and psychotic symptoms. This is very rare. Only one case is reported, so we do not know how common it is or what treatments work.

3

episodes of mood and psychotic symptoms

1

woman with PCOS

## About the study

Original title A case of repeated mixed mood episodes with psychotic symptoms associated with the premenstrual period in a patient with polycystic ovarian syndrome Authors Jalnapurkar I, Findley JC Journal Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Year 2018 Study design Case report What was tested None Read the paper [doi.org/10.1080/09513590.2017.1405930](https://doi.org/10.1080/09513590.2017.1405930)

## Topics

[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Schizophrenia and psychosis](https://niyora.com/research/topics/comorbidity-psychosis/)[Polycystic ovary syndrome (PCOS)](https://niyora.com/research/topics/comorbidity-pcos/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Study, 2026

Do anxiety and depression get worse before your period if you already have a mental health condition?

Survey study, 2026

What is the true rate of PMDD, and does it worsen mental health conditions?

Case-control study, 2021

Do women with PMDD have different brain responses to emotions?

Interview study, 2000

Are depression and personality disorders linked to PMDD?

Review, 2025

How does the menstrual cycle affect psychiatric symptoms like depression and anxiety?

Randomised trial, 2023

What does research show about PMDD neurochemistry?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗