---
title: What do we know about what causes PMS and PMDD? | Niyora
description: The exact causes aren't well understood yet. PMS and PMDD happen in the second half of your menstrual cycle and involve mood and physical symptoms.
url: https://niyora.com/research/papers/aetiology-diagnosis-and-management-of-premenstrual-changes-pmcs-current-views-2004/
---

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- What do we know about what causes PMS and PMDD?

Study, 2004

# What do we know about what causes PMS and PMDD?

The exact causes aren't well understood yet. PMS and PMDD happen in the second half of your menstrual cycle and involve mood and physical symptoms.

 Early or limited evidence

General information about PMS and PMDD

## What they did

Reviewed current research about what causes, diagnoses, and treats PMS and PMDD.

## What they found

PMS and PMDD happen during the luteal phase (ovulation to start of period). PMS involves mild mood changes while PMDD involves severe mental and physical symptoms. The exact cause remains largely unknown. Diagnosis and treatment are often difficult.

## What it means for you

Doctors and researchers still don't fully understand what causes these conditions, which is why they continue studying this area.

## About the study

Original title Aetiology, Diagnosis And Management Of Premenstrual Changes (Pmcs): Current Views Journal The Internet Journal of Gynecology and Obstetrics Year 2004 Study design Study What was tested No specific intervention Read the paper [doi.org/10.5580/1084](https://doi.org/10.5580/1084)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Cohort study, 2026

What genetic factors are linked to premenstrual symptoms?

Study, 2026

How do women with PMDD process emotions differently in their brains?

Systematic review, 2026

Why do some women experience mood changes linked to their menstrual cycle?

Case-control study, 2026

Do women with PMS handle emotions differently at different times of the cycle?

Survey study, 2025

Does PMDD or PMS affect quality of life?

Systematic review, 2025

Do people with PMDD and severe PMS have difficulties with emotion regulation?

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