---
title: Does agnus castus help with PMS? | Niyora
description: Yes, agnus castus was safe and effective for treating PMS in a randomized, blinded trial of 170 women, though this is based on one study.
url: https://niyora.com/research/papers/agnus-castus-fruit-extract-was-safe-and-effective-for-relieving-symptoms-of-2001/
---

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- Does agnus castus help with PMS?

Randomised trial, 2001

# Does agnus castus help with PMS?

Yes, agnus castus was safe and effective for treating PMS in a randomized, blinded trial of 170 women, though this is based on one study.

 Moderate study design

170 women with premenstrual syndrome (mean age 37 years)

## What they did

A randomized, blinded, placebo-controlled trial in 6 outpatient clinics. 178 women age 18 and older with PMS received either agnus castus 20 mg daily or placebo for three consecutive menstrual cycles. 170 women completed the study.

## What they found

Agnus castus was safe and effective for treating premenstrual syndrome symptoms. The study used strict criteria to select women with PMS and excluded women with hormonal disorders, serious medical conditions, or those taking sex hormones.

## What it means for you

Agnus castus appears to be a safe herbal option for PMS. However, only one study has tested it this way, and the specific numbers for how much each symptom improved are not provided in this summary. More research would strengthen the evidence and clarify which symptoms it helps most.

170

Women who completed the study

37 years

Mean age

20 mg

Daily dose of agnus castus

## About the study

Original title Agnus castus fruit extract was safe and effective for relieving symptoms of premenstrual syndrome Authors BMJ Publishing Group Ltd and RCN Publishing Company Ltd Journal Evidence-Based Nursing Year 2001 Study design Randomised trial Participants 91 What was tested Agnus castus 20 mg daily vs placebo Read the paper [doi.org/10.1136/ebn.4.4.114](https://doi.org/10.1136/ebn.4.4.114)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Psychotherapy, counselling and education](https://niyora.com/research/topics/treatment-psychotherapy/)[Vitex agnus-castus (chasteberry)](https://niyora.com/research/topics/treatment-vitex/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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