---
title: Do women with PMDD have weaker bones? | Niyora
description: No, women with PMDD have normal bone density for their age, no different from women without PMDD.
url: https://niyora.com/research/papers/are-women-with-premenstrual-dysphoric-disorder-prone-to-osteoporosis-2001/
---

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- Do women with PMDD have weaker bones?

Cohort study, 2001

# Do women with PMDD have weaker bones?

No, women with PMDD have normal bone density for their age, no different from women without PMDD.

 Early or limited evidence

38 healthy women (20 with PMDD, 18 without)

## What they did

Researchers measured bone density at three locations (lower spine and hip) in 20 women with PMDD and 18 women without PMDD using x-ray imaging.

## What they found

Both groups had bone density as expected for their age and sex. The PMDD and control groups did not differ in bone density or Z scores at any of the three sites studied.

## What it means for you

This study found no evidence that PMDD increases osteoporosis risk. However, the study is very small, so larger studies are needed to confirm this finding.

20

women with PMDD

18

control women

3

bone sites measured

## About the study

Original title Are women with premenstrual dysphoric disorder prone to osteoporosis? Authors Halbreich U, Kahn LS Journal Psychosomatic medicine Year 2001 Study design Cohort study What was tested None (comparison study) Read the paper [doi.org/10.1097/00006842-200105000-00005](https://doi.org/10.1097/00006842-200105000-00005)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Cohort study, 2026

What genetic factors are linked to premenstrual symptoms?

Systematic review, 2026

How often do mood disorders and PMS or PMDD occur together?

Review, 2024

What are the most effective treatments for PMDD?

Systematic review, 2024

How common is PMDD?

Systematic review, 2021

Are there hormone changes that could explain PMDD or depression in women?

Non-randomised trial, 2008

Can the Sheehan Disability Scale measure whether treatments work?

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