---
title: What causes PMS and how is it treated? | Niyora
description: PMS is caused by changes in hormone levels affecting brain chemicals like serotonin. New treatments that have been tested in careful studies are now available
url: https://niyora.com/research/papers/assessment-and-management-of-premenstrual-syndrome-1992/
---

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- What causes PMS and how is it treated?

Review, 1992

# What causes PMS and how is it treated?

PMS is caused by changes in hormone levels affecting brain chemicals like serotonin. New treatments that have been tested in careful studies are now available.

 Moderate study design

Review of PMS research

## What they did

Review of scientific research on PMS causes, diagnosis, and treatments.

## What they found

PMS is caused by the interaction of cyclic estrogen and progesterone changes with multiple body systems, especially neurotransmitters. Serotonin appears especially important. Specific treatments have been developed that work in careful and reproducible studies.

## What it means for you

Our understanding of PMS has improved and there are now proven treatments available. The main limit is that this reviews existing research rather than presenting new findings.

## About the study

Original title Assessment and management of premenstrual syndrome Authors Mortola JF Journal Current opinion in obstetrics & gynecology Year 1992 Study design Review What was tested None (literature review) Read the paper [doi.org/10.1097/00001703-199212000-00017](https://doi.org/10.1097/00001703-199212000-00017)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)

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