--- title: Are PMDD symptoms linked to depression and anxiety? | Niyora description: Yes. Women with higher PMDD-type symptom scores were much more likely to have depression and anxiety, and most women with PMDD had severe depression and moder url: https://niyora.com/research/papers/association-of-premenstrual-dysphoric-disorder-with-depression-and-anxiety-in-2025/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Are PMDD symptoms linked to depression and anxiety? Survey study, 2025 # Are PMDD symptoms linked to depression and anxiety? Yes. Women with higher PMDD-type symptom scores were much more likely to have depression and anxiety, and most women with PMDD had severe depression and moderate-to-high anxiety. Early or limited evidence 100 women aged 15 to 49 in India with PMDD-like symptoms ## What they did Cross-sectional study of 100 women aged 15 to 49 at a gynaecology outpatient clinic in Hapur, India, from August 2024 to January 2025, all with PMDD-like symptoms. They were scored on a symptom tool (PSST) and on standard depression and anxiety scales (BDI, BAI). Tests checked links between symptom scores, depression, anxiety, education and menstrual flow. ## What they found 65 of the 100 women were diagnosed with PMDD and 35 had mild PMS. Symptom scores differed significantly by education level (p=0.01) and amount of menstrual flow (p=0.006), and duration of menstrual flow predicted symptom severity (p=0.04). PMDD symptom scores were strongly linked to depression (p<0.001) and anxiety (p<0.001), with most PMDD women having severe depression and moderate-to-high anxiety. ## What it means for you PMDD appears closely tied to depression and anxiety severity in this group, and lower education and heavier or longer periods seem to make symptoms worse. The study is small, from a single hospital in India, and cross-sectional, so it cannot show which problem causes which. 65/100 diagnosed with PMDD 84.22 link to depression (chi2) 64.84 link to anxiety (chi2) ## About the study Original title Association of Premenstrual Dysphoric Disorder with Depression and Anxiety in Women of Reproductive Age Group: A Cross-sectional Study Authors Manisha Upadhyay, Saurav Kumar, Meenu Saini et al. Journal JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH Year 2025 Study design Survey study Participants 100 What was tested None (observational screening study, no treatment tested) Open access Yes Read the paper [doi.org/10.7860/jcdr/2025/80492.21470](https://doi.org/10.7860/jcdr/2025/80492.21470) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Work and productivity](https://niyora.com/research/topics/life-area-work/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Study, 2026 What are premenstrual syndrome and premenstrual dysphoric disorder? Survey study, 2008 Do healthy women without PMDD have mood changes during their menstrual cycle? Systematic review, 2026 Why do some women experience mood changes linked to their menstrual cycle? Review, 2015 What do we know about PMS and PMDD and how are they treated? Review, 2008 What medications are FDA-approved for treating PMDD? Randomised trial, 1995 Does fluoxetine help premenstrual dysphoria? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗