---
title: Do electrolyte levels in the blood affect PMS symptoms? | Niyora
description: Women with PMS had significantly higher serum sodium levels than those without PMS. However, this was a very small study from one hospital, so we cannot be co
url: https://niyora.com/research/papers/association-of-serum-electrolytes-level-with-premenstrual-syndrome-2024/
---

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- Do electrolyte levels in the blood affect PMS symptoms?

Survey study, 2024

# Do electrolyte levels in the blood affect PMS symptoms?

Women with PMS had significantly higher serum sodium levels than those without PMS. However, this was a very small study from one hospital, so we cannot be confident the results apply more broadly.

 Early or limited evidence

30 young unmarried women in Dhaka, Bangladesh

## What they did

Researchers measured serum sodium and potassium levels in 30 young women and compared levels in women with and without PMS symptoms during different phases of the menstrual cycle.

## What they found

Mean serum sodium was 139.97±1.30 mmol/L in one group and 140.93±1.68 mmol/L in the other, with the PMS group having significantly higher sodium (p<0.05). Serum potassium was 4.20±0.32 and 4.17±0.31 mmol/L. PMS-related symptoms including irritability, bloating, backache, depression, fatigue, breast tenderness, headache, and anxiety were significantly higher during the luteal phase than the postmenstrual phase (p<0.05).

## What it means for you

Sodium levels may play a role in PMS symptoms. However, this was an extremely small study from one hospital in Bangladesh, so we cannot be confident these findings are accurate or that they apply elsewhere.

139.97±1.30

serum sodium group A (mmol/L)

140.93±1.68

serum sodium group B (mmol/L)

30

participants

## About the study

Original title Association of Serum Electrolytes Level with Premenstrual Syndrome Authors Jumana Rajia, Mahmuda Begum, Rozina Yasmin Choudhury et al. Journal Z H Sikder Women’s Medical College Journal Year 2024 Study design Survey study Participants 30 What was tested None Open access Yes Read the paper [doi.org/10.47648/zhswmcj.2024.v0601.03](https://doi.org/10.47648/zhswmcj.2024.v0601.03) Original abstract

Background: Premenstrual syndrome (PMS) is a significant health condition that affects a significant portion ofthe female population. Due to the ovarian hormone, changes in serum electrolyte levels can happen in the late lutealperiod of the menstrual cycle. Methods: A cross-sectional study was conducted to find out the association of serum electrolytes levels of 30 youngunmarried women with PMS from July 2016 to June 2017 in the Department of Physiology, Sir Salimullah MedicalCollege, Dhaka, Bangladesh. Results: The mean age of both groups of young unmarried women of was 20.30±1.15 years and 20.53±1.17 years. Themean serum sodium level was 139.97±1.30 and 140.93±1.68 mmol/L, and the serum potassium level was 4.20±0.32and 4.17±0.31 mmol/L. The mean serum sodium level was significantly higher in group B in comparison to groupA (p<0.05). Premenstrual scores of irritability, abdominal bloating, backache, depression, fatigue, breast tenderness,headache, and anxiety were significantly higher in comparison to those of postmenstrual scores in the PMS group(p<0.05). Conclusion: These study results acclaimed that serum sodium levels influence the physical and psychological symptoms of women with PMS.

Reproduced under CC-BY.

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Bloating, breast tenderness and physical symptoms](https://niyora.com/research/topics/symptom-physical-symptoms/)

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