--- title: Do adolescents with PMS have different blood pressure patterns across the menstrual cycle? description: Adolescents with and without PMS had similar overall blood pressure readings. However, within the PMS group, blood pressure changed across the cycle, with hig url: https://niyora.com/research/papers/blood-pressure-patterns-in-adolescents-with-premenstrual-syndrome-office-home-2026/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Do adolescents with PMS have different blood pressure patterns across the menstrual cycle? Cohort study, 2026 # Do adolescents with PMS have different blood pressure patterns across the menstrual cycle? Adolescents with and without PMS had similar overall blood pressure readings. However, within the PMS group, blood pressure changed across the cycle, with higher systolic blood pressure during the luteal phase. The clinical significance is unclear. Early or limited evidence 31 adolescents with PMS (mean age 15.61 ± 1.42 years) and 21 without PMS (mean age 14.82 ± 1.40 years) ## What they did Cohort study comparing 31 adolescents with PMS and 21 without PMS (ages 12-18). Blood pressure was measured in three ways: office readings, 7-day home monitoring, and 24-hour ambulatory monitoring. All measurements were taken during both follicular and luteal phases of the menstrual cycle. ## What they found The PMS and non-PMS groups had similar office blood pressure and 7-day home readings in both phases. Within the PMS group, 7-day home monitoring showed higher morning and mean systolic blood pressure during the luteal phase (p=0.001 and p=0.006). 24-hour ambulatory monitoring showed lower daytime diastolic blood pressure and higher pulse pressure during the luteal phase (p=0.029 and p=0.018). ## What it means for you The menstrual cycle may influence blood pressure regulation in adolescents with PMS. However, the differences were small and their clinical importance is unclear. The study was small with measurements from only one or two cycles, so larger longitudinal studies are needed to determine significance. 31 adolescents with PMS 15.61 ± 1.42 mean age with PMS, years p=0.001 higher systolic BP during luteal phase ## About the study Original title Blood pressure patterns in adolescents with premenstrual syndrome: office, home, and ambulatory blood pressure monitoring across the menstrual cycle Authors Akbulut O, Akgül S, Pehlivantürk-Kızılkan M et al. Journal Pediatric nephrology (Berlin, Germany) Year 2026 Study design Cohort study Participants 31 What was tested None - observational cohort study Open access Yes Read the paper [doi.org/10.1007/s00467-026-07517-x](https://doi.org/10.1007/s00467-026-07517-x) Original abstract Background: Premenstrual syndrome (PMS) has been associated with dysregulation of the renin-angiotensin-aldosterone system (RAAS), a pathway also implicated in hypertension. Evaluation of blood pressure (BP) patterns in adolescents with PMS may therefore clarify shared neuroendocrine and vascular mechanisms. This study aimed to compare BP profiles in adolescents with and without PMS and to assess phase-specific BP variations across the menstrual cycle. Methods: Adolescents aged 12-18 years with regular menstrual cycles for at least three months were enrolled. PMS was assessed using the Gencdogan Premenstrual Syndrome Scale (PMSS). Office BP measurements (OBPM), 7-day home BP monitoring (HBPM), and 24-h ambulatory BP monitoring (ABPM) were conducted during the follicular and luteal phases. Results: The study included 31 adolescents with PMS (mean age 15.61 ± 1.42 years) and 21 without PMS (mean age 14.82 ± 1.40 years). PMS ( +) and PMS ( -) groups were comparable regarding office BP, 7-day HBPM, and 24-h ABPM in both phases. Within the PMS group, 7-day HBPM demonstrated significantly higher morning and mean systolic BP during the luteal phase compared with the follicular phase (p = 0.001 and p = 0.006, respectively). Conversely, 24-h ABPM showed lower 24-h and daytime diastolic BP (p = 0.029 and p = 0.019, respectively) and higher pulse pressure (p = 0.018) during the luteal phase. Conclusions: Adolescents with and without PMS showed broadly similar BP values. However, statistically significant phase-related changes in systolic and diastolic BP were observed within the PMS group, suggesting that menstrual cycle-related physiological variation may influence BP regulation in these adolescents. Larger longitudinal studies are needed to determine the clinical significance and underlying mechanisms of these findings. Reproduced under CC-BY. ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2026 Does aerobic or resistance exercise reduce anxiety in women with PMS? Cohort study, 2025 How common is PMS in Chinese teenage girls, and what factors are linked to it? 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