---
title: Can citalopram, an antidepressant, help premenstrual dysphoria?
description: Yes, citalopram is an antidepressant shown in controlled trials to help premenstrual dysphoria, depression, anxiety, and other conditions. This review focuses
url: https://niyora.com/research/papers/citalopram-a-comprehensive-review-2001/
---

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- Can citalopram, an antidepressant, help premenstrual dysphoria?

Review, 2001

# Can citalopram, an antidepressant, help premenstrual dysphoria?

Yes, citalopram is an antidepressant shown in controlled trials to help premenstrual dysphoria, depression, anxiety, and other conditions. This review focuses on the drug's general benefits, not specifically on PMS.

 Early or limited evidence

Various patient groups including those with premenstrual dysphoria

## What they did

Review of clinical trials testing citalopram for various conditions.

## What they found

Citalopram has demonstrated antidepressant efficacy in numerous controlled clinical trials. The drug also benefits patients with anxiety, panic disorder, obsessive-compulsive disorder, premenstrual dysphoria, alcohol dependence, and behavioral disturbances of dementia.

## What it means for you

Citalopram appears to help severe PMS (premenstrual dysphoria) along with depression and anxiety. However, this review focuses on the drug's general uses, not specifically on how well it works for PMS.

## About the study

Original title Citalopram: a comprehensive review Authors Pollock BG Journal Expert opinion on pharmacotherapy Year 2001 Study design Review What was tested Citalopram treatment Read the paper [doi.org/10.1517/14656566.2.4.681](https://doi.org/10.1517/14656566.2.4.681)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Anxiety disorders and OCD](https://niyora.com/research/topics/comorbidity-anxiety-disorders/)[Alcohol, smoking and substance use](https://niyora.com/research/topics/comorbidity-substance-use/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Review, 2000

What conditions beyond depression can antidepressants treat?

Survey study, 2001

How common is premenstrual dysphoric disorder and how is it related to other psychiatric conditions?

Randomised trial, 1999

Do SSRIs reduce premenstrual dysphoria symptoms?

Study, 2026

Do anxiety and depression get worse before your period if you already have a mental health condition?

Cohort study, 2019

Do SSRIs help women who have both PMS and panic disorder?

Cohort study, 2012

How quickly does fluoxetine start working for PMDD symptoms?

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