---
title: Does black cohosh cause blood clots and fluid retention? | Niyora
description: One woman using black cohosh developed blood clots, fluid retention, and liver inflammation. This is rare, but doctors should consider it in women with these
url: https://niyora.com/research/papers/coagulation-activation-and-fluid-retention-associated-with-the-use-of-black-2010/
---

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- Does black cohosh cause blood clots and fluid retention?

Case report, 2010

# Does black cohosh cause blood clots and fluid retention?

One woman using black cohosh developed blood clots, fluid retention, and liver inflammation. This is rare, but doctors should consider it in women with these symptoms who are using black cohosh.

 Early or limited evidence

Woman using black cohosh for menopausal symptoms

## What they did

Case report describing one woman who used black cohosh for menopausal symptoms and developed serious side effects.

## What they found

She developed coagulation activation (blood clot formation), fluid retention in her lower legs, and transient liver inflammation.

## What it means for you

Black cohosh is usually well tolerated. However, it can occasionally cause serious complications including blood clots and leg swelling. Women using black cohosh who develop leg swelling should seek medical attention. This is based on one case, so we don't know how often this happens.

1

case reported

## About the study

Original title Coagulation activation and fluid retention associated with the use of black cohosh: a case study Authors Zimmermann R, Witte A, Voll RE et al. Journal Climacteric : the journal of the International Menopause Society Year 2010 Study design Case report What was tested Black cohosh Read the paper [doi.org/10.3109/13697130902939921](https://doi.org/10.3109/13697130902939921)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)[Perimenopause and menopause](https://niyora.com/research/topics/comorbidity-perimenopause/)

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