--- title: Can propolis and fennelin reduce PMS symptoms? | Niyora description: Yes, both propolis and fennelin reduced PMS symptom severity by about 79%, significantly better than placebo, but the study only lasted 2 menstrual cycles. url: https://niyora.com/research/papers/comparison-of-the-effects-of-propolis-and-fennelin-capsules-on-premenstrual-2026/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Can propolis and fennelin reduce PMS symptoms? Randomised trial, 2026 # Can propolis and fennelin reduce PMS symptoms? Yes, both propolis and fennelin reduced PMS symptom severity by about 79%, significantly better than placebo, but the study only lasted 2 menstrual cycles. Moderate study design 90 female university students with PMS at Hamadan University of Medical Sciences ## What they did A double-blind, randomized controlled trial with 90 female university students. They were randomly assigned to propolis 500 mg (30 women), fennelin 30 mg extract (30 women), or placebo (30 women). Treatment lasted 2 menstrual cycles. PMS symptoms were measured using questionnaires. ## What they found Propolis reduced PMS symptom severity by 78.9% and fennelin by 79.3% (p = 0.016), both significantly better than placebo. Placebo showed no significant change (p = 0.206). No side effects were reported. ## What it means for you Propolis and fennelin may help reduce PMS symptoms in young women. The main limits are the short study duration (only 2 cycles), the young age of participants (university students), and small sample size, so results may not apply to older women with more severe PMS. 90 Women in study 78.9% PMS symptom reduction with propolis 79.3% PMS symptom reduction with fennelin ## About the study Original title Comparison of the Effects of Propolis and Fennelin Capsules on Premenstrual Syndrome in Students: A Randomized Clinical Trial Authors Shayan A, Tiznobik A, Refaei M et al. Journal Reviews on recent clinical trials Year 2026 Study design Randomised trial Participants 90 What was tested Propolis 500 mg vs fennelin 30 mg extract vs placebo Read the paper [doi.org/10.2174/0115748871406071251122055743](https://doi.org/10.2174/0115748871406071251122055743) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)[Students and academic performance](https://niyora.com/research/topics/life-area-education/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2025 Which is more effective for PMS - Vitagnus, soy, or both together? Survey study, 2026 How common is PMDD among female medical students and what triggers it? Randomised trial, 2024 Does a herbal soft gel capsule with three oils reduce PMS symptoms? Randomised trial, 2021 Does nigella sativa oil reduce PMS symptoms? Randomised trial, 2020 Does anise reduce PMS symptoms? Randomised trial, 2020 Does Echium amoenum herb help reduce PMS symptoms? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗