---
title: Does Lactobacillus gasseri CP2305 help premenstrual symptoms?
description: It may help mood and anxiety symptoms before your period, but it does not help water retention symptoms like breast swelling.
url: https://niyora.com/research/papers/daily-intake-of-lactobacillus-gasseri-cp2305-ameliorates-psychological-2021/
---

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- Does Lactobacillus gasseri CP2305 help premenstrual symptoms?

Randomised trial, 2021

# Does Lactobacillus gasseri CP2305 help premenstrual symptoms?

It may help mood and anxiety symptoms before your period, but it does not help water retention symptoms like breast swelling.

 Moderate study design

56 healthy young women

## What they did

56 healthy young women took either Lactobacillus gasseri CP2305 or placebo tablets daily for 6 menstrual cycles. Researchers measured premenstrual symptoms and hormone levels.

## What they found

Women in the CP2305 group reported fewer overall premenstrual symptoms, especially psychological ones like depressed mood and anxiety, compared to placebo. However, water retention symptoms like breast tenderness and swelling improved only in the placebo group. The CP2305 group had higher reproductive hormone levels during the second half of their cycle.

## What it means for you

This probiotic might help psychological symptoms before your period but not physical swelling. It may work by changing hormone levels. This was a small study so larger studies are needed to confirm the findings.

56

women studied

6

menstrual cycles

mood improved

with CP2305 vs placebo

## About the study

Original title Daily intake of Lactobacillus gasseri CP2305 ameliorates psychological premenstrual symptoms in young women: A randomized, double-blinded, placebo-controlled study Authors Kensei Nishida, Daisuke Sawada, Toshiyuki Yasui et al. Journal Journal of Functional Foods Year 2021 Study design Randomised trial What was tested Lactobacillus gasseri CP2305 versus placebo, taken daily for 6 menstrual cycles Open access Yes Read the paper [doi.org/10.1016/j.jff.2021.104426](https://doi.org/10.1016/j.jff.2021.104426)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Bloating, breast tenderness and physical symptoms](https://niyora.com/research/topics/symptom-physical-symptoms/)[Work and productivity](https://niyora.com/research/topics/life-area-work/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/)

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