---
title: Does vitamin D intake reduce the risk of PMS? | Niyora
description: Higher vitamin D intake from food may be linked to lower PMS risk, though the evidence is weak and larger studies are needed to confirm.
url: https://niyora.com/research/papers/dietary-vitamin-d-intake-25-hydroxyvitamin-d3-levels-and-premenstrual-syndrome-2010/
---

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- Does vitamin D intake reduce the risk of PMS?

Case-control study, 2010

# Does vitamin D intake reduce the risk of PMS?

Higher vitamin D intake from food may be linked to lower PMS risk, though the evidence is weak and larger studies are needed to confirm.

 Early or limited evidence

186 college-aged women aged 18-30, including 44 with PMS and 46 without PMS

## What they did

Cross-sectional study (2006-2008) of 186 college-aged women (mean age 21.6 years). Participants completed a food frequency questionnaire and symptom questionnaire, and provided a blood sample during the late luteal phase. Researchers compared 44 with PMS to 46 without PMS.

## What they found

In all participants, possible link between higher vitamin D intake and lower symptom severity (mean intakes 253, 214, and 194 IU/day for none/minimal, mild, and moderate/severe symptoms, P=0.18, not significant). In case-control analysis, women with vitamin D intake ≥100 IU/day had an odds ratio of 0.31 compared to <100 IU/day (95% CI 0.10-0.98). Blood vitamin D levels measured during late luteal phase were not associated with PMS.

## What it means for you

Small pilot study with limited power. Blood vitamin D level at one time point was not useful for predicting PMS. Larger studies are needed to confirm the possible protective effect of dietary vitamin D.

253-194

mean vitamin D in none/minimal vs moderate/severe symptoms

0.31

odds ratio for PMS with ≥100 vs <100 IU/day vitamin D

186

total women studied

## About the study

Original title Dietary vitamin D intake, 25-hydroxyvitamin D3 levels and premenstrual syndrome in a college-aged population Authors Bertone-Johnson ER, Chocano-Bedoya PO, Zagarins SE et al. Journal The Journal of steroid biochemistry and molecular biology Year 2010 Study design Case-control study Participants 186 What was tested Vitamin D intake Read the paper [doi.org/10.1016/j.jsbmb.2010.03.076](https://doi.org/10.1016/j.jsbmb.2010.03.076)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Calcium](https://niyora.com/research/topics/treatment-calcium/)[Vitamin D](https://niyora.com/research/topics/treatment-vitamin-d/)[Relationships and partners](https://niyora.com/research/topics/life-area-relationships/)[Students and academic performance](https://niyora.com/research/topics/life-area-education/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/)

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