---
title: Does the menstrual cycle affect mood disorders? | Niyora
description: Some women with mood disorders may experience worsening symptoms during the premenstrual period. Evidence is limited and study methods are inconsistent across
url: https://niyora.com/research/papers/does-menstrual-cycle-affect-mood-disorders-2006/
---

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- Does the menstrual cycle affect mood disorders?

Survey study, 2006

# Does the menstrual cycle affect mood disorders?

Some women with mood disorders may experience worsening symptoms during the premenstrual period. Evidence is limited and study methods are inconsistent across available research.

 Early or limited evidence

Literature review (not an original study of patients)

## What they did

Literature review of studies from 1955 to 2005 on the relationship between menstrual cycle, mood disorders, and suicide.

## What they found

Reports showed higher psychiatric hospital admissions during the premenstrual period and suicide attempts during specific menstrual cycle phases in women of reproductive age with mental disorders. Limited data on bipolar disorder direction. Findings were inconsistent across studies.

## What it means for you

There may be a link between menstrual cycle and mood exacerbation in some women, especially the premenstrual period for depression. However, existing studies are small, lack prospective design, and use unreliable methods to track cycle phases. Much better research is needed.

## About the study

Original title [Does menstrual cycle affect mood disorders?] Authors Akdeniz F, Karadağ F Journal Turk psikiyatri dergisi = Turkish journal of psychiatry Year 2006 Study design Survey study What was tested None (literature review only) Read the paper [https://pubmed.ncbi.nlm.nih.gov/17183446/](https://pubmed.ncbi.nlm.nih.gov/17183446/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Premenstrual exacerbation (PME)](https://niyora.com/research/topics/condition-pme/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Suicidality](https://niyora.com/research/topics/symptom-suicidality/)[Bipolar disorder](https://niyora.com/research/topics/comorbidity-bipolar/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)[Relationships and partners](https://niyora.com/research/topics/life-area-relationships/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Study, 2026

Do anxiety and depression get worse before your period if you already have a mental health condition?

Cohort study, 2023

Does the menstrual cycle affect how often women have suicidal thoughts?

Study, 2026

What are premenstrual syndrome and premenstrual dysphoric disorder?

Survey study, 2026

What is the true rate of PMDD, and does it worsen mental health conditions?

Cohort study, 2024

Does the menstrual cycle affect daily changes in suicidal thoughts?

Review, 2025

How does the menstrual cycle affect psychiatric symptoms like depression and anxiety?

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