--- title: Does a drospirenone birth control pill improve premenstrual symptoms and wellbeing? description: Yes, most women in this study reported a big improvement in premenstrual symptoms and their general wellbeing scores rose significantly after six cycles of ta url: https://niyora.com/research/papers/effect-of-a-combination-of-ethinylestradiol-30-microg-and-drospirenone-3-mg-on-2006/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does a drospirenone birth control pill improve premenstrual symptoms and wellbeing? Non-randomised trial, 2006 # Does a drospirenone birth control pill improve premenstrual symptoms and wellbeing? Yes, most women in this study reported a big improvement in premenstrual symptoms and their general wellbeing scores rose significantly after six cycles of taking this pill. Moderate study design 241 healthy women with premenstrual disorder symptoms seeking contraception ## What they did 241 healthy women with premenstrual disorder symptoms who wanted contraception took a combined pill with ethinylestradiol 30 micrograms and drospirenone 3 mg for six menstrual cycles. 203 completed all six cycles and were assessed for how well it worked, while 236 were checked for side effects. Wellbeing was measured with a standard questionnaire. ## What they found General wellbeing scores were significantly higher after six cycles compared to the start. 198 women (84.2%) reported great improvement in premenstrual symptoms. Body weight and blood pressure did not change significantly, and side effects were the kind already known with this type of pill. ## What it means for you This pill appears to ease premenstrual symptoms and support wellbeing while providing reliable cycle control, with side effects similar to other birth control pills. There was no separate comparison group given a different treatment or a placebo, so the improvement cannot be fully separated from other possible influences. 84.2% Reported great symptom improvement 203 Completed all six cycles 241 Total enrolled ## About the study Original title Effect of a combination of ethinylestradiol 30 microg and drospirenone 3 mg on tolerance, cycle control, general well-being and fluid-related symptoms in women with premenstrual disorders requesting contraception Authors Borges LE, Andrade RP, Aldrighi JM et al. Journal Contraception Year 2006 Study design Non-randomised trial Participants 241 What was tested Combined oral contraceptive pill with ethinylestradiol 30 micrograms and drospirenone 3 mg, taken for six cycles Read the paper [doi.org/10.1016/j.contraception.2005.10.016](https://doi.org/10.1016/j.contraception.2005.10.016) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[Quality of life and daily functioning](https://niyora.com/research/topics/life-area-quality-of-life/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Systematic review, 2020 How common is PMS among women of reproductive age in Ethiopia? Randomised trial, 2011 Does a 24/4 birth control pill help women with PMDD improve work, relationship, and social functioning? Review, 2009 What causes PMDD and what are the treatment options? Randomised trial, 2004 Which low-dose birth control pill has better cycle control and fewer side effects? Study, 2026 What treatments work for PMDD? Survey study, 2026 How common is PMS in female medical students and how much does it affect their daily life? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗