---
title: Do omega-3 supplements help reduce PMS? | Niyora
description: Yes, omega-3 fatty acids appear to reduce PMS severity overall and specifically reduce both body-related and mood-related symptoms. The benefit increased with
url: https://niyora.com/research/papers/effect-of-omega-3-fatty-acids-on-premenstrual-syndrome-a-systematic-review-and-2022/
---

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- Do omega-3 supplements help reduce PMS?

Systematic review, 2022

# Do omega-3 supplements help reduce PMS?

Yes, omega-3 fatty acids appear to reduce PMS severity overall and specifically reduce both body-related and mood-related symptoms. The benefit increased with longer treatment duration.

 Moderate study design

Women with PMS (randomized clinical trials)

## What they did

Systematic review and meta-analysis of randomized clinical trials investigating omega-3 fatty acids for PMS. Databases were searched for relevant studies. Randomized trials meeting inclusion criteria were analyzed. Results were combined using meta-analysis, and factors affecting outcomes were examined.

## What they found

Omega-3 reduced overall PMS severity (standardized mean difference -0.968). It reduced body-related symptoms (standardized mean difference -0.800) and mood-related symptoms (standardized mean difference -0.373). Age and longer treatment duration both increased the treatment effect. However, there was high variability between studies (I-squared 89.11%), indicating conflicting results.

## What it means for you

Omega-3 may help with PMS, particularly body and mood symptoms. However, there is high variability between studies, suggesting results may differ across populations. Longer treatment duration appeared to increase effectiveness. The authors urge caution given the conflicting results between studies.

-0.968

standardized mean difference for overall PMS severity

89.11%

heterogeneity showing high variability between studies

-0.800

standardized mean difference for body symptoms

## About the study

Original title Effect of omega-3 fatty acids on premenstrual syndrome: A systematic review and meta-analysis Authors Mohammadi MM, Dehghan Nayeri N, Mashhadi M et al. Journal The journal of obstetrics and gynaecology research Year 2022 Study design Systematic review What was tested Omega-3 fatty acids Read the paper [doi.org/10.1111/jog.15217](https://doi.org/10.1111/jog.15217)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Omega-3 fatty acids](https://niyora.com/research/topics/treatment-omega-3/)

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