---
title: Does taking zinc supplements help with PMS symptoms? | Niyora
description: Yes, the evidence so far suggests zinc supplements can reduce overall PMS symptoms, including emotional and physical ones, but the research base is still smal
url: https://niyora.com/research/papers/effect-of-zinc-supplementation-on-premenstrual-symptoms-a-systematic-review-and-2025/
---

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- Does taking zinc supplements help with PMS symptoms?

Systematic review, 2025

# Does taking zinc supplements help with PMS symptoms?

Yes, the evidence so far suggests zinc supplements can reduce overall PMS symptoms, including emotional and physical ones, but the research base is still small so this isn't fully settled.

 Moderate study design

Women of reproductive age with PMS, pooled across five randomized controlled trials

## What they did

Researchers combined results from existing studies on zinc for PMS. They searched six databases and found five randomized controlled trials; five were reviewed in detail and four of those were combined in a statistical analysis (meta-analysis).

## What they found

Zinc supplementation reduced total PMS scores (effect size g = -0.384), emotional symptoms (g = -0.347), and physical symptoms (g = -0.512), with all results favoring zinc over the comparison. The reduction in total PMS scores and emotional symptoms was supported by moderate-certainty evidence; the physical symptom result was weaker (low certainty) and more sensitive to which studies were included.

## What it means for you

Zinc looks like a promising, non-drug option for easing PMS symptoms, but only five trials exist and they varied in quality and methods, so larger, better-designed studies are needed before this can be recommended with confidence.

5

trials included in the review

g = -0.384

effect size for total PMS score reduction

g = -0.512

effect size for physical symptom reduction

## About the study

Original title Effect of zinc supplementation on premenstrual symptoms: A systematic review and meta-analysis Authors Kim YM, Baek J Journal Women & health Year 2025 Study design Systematic review What was tested Zinc supplementation Read the paper [doi.org/10.1080/03630242.2025.2539815](https://doi.org/10.1080/03630242.2025.2539815)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Zinc and iron](https://niyora.com/research/topics/treatment-zinc-iron/)[Work and productivity](https://niyora.com/research/topics/life-area-work/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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