---
title: Does Persian Golnar work as well as tranexamic acid for heavy menstrual bleeding?
description: Yes. Both Persian Golnar and tranexamic acid significantly reduced heavy bleeding and improved quality of life and premenstrual symptoms. Persian Golnar appea
url: https://niyora.com/research/papers/effectiveness-of-persian-golnar-on-excessive-menstrual-bleeding-in-women-with-2023/
---

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- Does Persian Golnar work as well as tranexamic acid for heavy menstrual bleeding?

Randomised trial, 2023

# Does Persian Golnar work as well as tranexamic acid for heavy menstrual bleeding?

Yes. Both Persian Golnar and tranexamic acid significantly reduced heavy bleeding and improved quality of life and premenstrual symptoms. Persian Golnar appeared equally effective as tranexamic acid in this reasonably well-designed trial.

 Moderate study design

80 women (76 completed) with abnormal uterine bleeding

## What they did

Triple-blind randomized controlled trial of 80 women with abnormal uterine bleeding (76 completed). Women were randomly assigned to receive either Persian Golnar or tranexamic acid daily for 3 consecutive menstrual cycles. Blood loss was measured using the Pictorial Blood Loss Assessment Chart. Quality of life and premenstrual symptoms were also assessed.

## What they found

Both groups experienced significant reduction in blood loss. Hemoglobin level increased significantly in the Persian Golnar group. Quality of life and premenstrual symptoms improved in both groups. Persian Golnar was as effective as tranexamic acid.

## What it means for you

Persian Golnar appears to be an effective herbal alternative to tranexamic acid for heavy menstrual bleeding. The trial was reasonably sized (80 women) but relatively short (12 weeks), so longer-term safety and effectiveness are unknown. Results may be specific to this product and population.

80

Participants enrolled

76

Participants completed

3

Menstrual cycles studied

## About the study

Original title Effectiveness of Persian Golnar on Excessive Menstrual Bleeding in Women with Abnormal Uterine Bleeding, Compared to Tranexamic Acid: A Triple-Blind, Randomized Equivalence Trial Authors Es-Haghee Ashteany S, Vahid Dastjerdi M, Tabarrai M et al. Journal Evidence-based complementary and alternative medicine : eCAM Year 2023 Study design Randomised trial Participants 80 What was tested Persian Golnar versus tranexamic acid, taken daily for 3 menstrual cycles Open access Yes Read the paper [doi.org/10.1155/2023/5355993](https://doi.org/10.1155/2023/5355993) Original abstract

Introduction: Abnormal uterine bleeding (AUB) is a major healthcare problem in females of reproductive age and impacts women's health and quality of life (QoL). This study aimed to test the equivalence of Persian Golnar (PG) and tranexamic acid (TA) for the treatment of excessive menstrual bleeding. Method: A triple-blind randomized equivalence trial with parallel design and block randomization technique was performed. A total of 80 patients with AUB were randomly allocated to receive either PG or TA for three consecutive menstrual cycles. Blood loss was measured by the Pictorial Blood Loss Assessment Chart (PBAC). Hematological evaluations were done before the intervention and after treatment. QoL and premenstrual dysphoric disorder (PMDD) as secondary outcomes were assessed using the menorrhagia questionnaire (MQ) and Premenstrual Symptoms Screening Tool (PSST). Statistical analysis was performed using an independent t -test, paired t -test, χ 2 test, Mann-Whitney test, and Wilcoxon signed-rank test. Results: Seventy-six women completed the 12-week follow-up. Both PG and TA groups experienced a significant reduction in blood loss. Furthermore, the serum level of hemoglobin in the PG group enhanced significantly ( P P < 0.001). Conclusion: The findings of the current trial supposed that the Golnar product is as effective as tranexamic acid in controlling bleeding and enhancing the quality of life and premenstrual symptoms.

Reproduced under CC-BY.

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Quality of life and daily functioning](https://niyora.com/research/topics/life-area-quality-of-life/)

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