--- title: Does pumpkin seed extract reduce PMS symptoms in teenage girls? description: Yes. Taking 500 mg of pumpkin seed extract twice daily for 10 days significantly reduced PMS symptoms more than taking it once daily or placebo. url: https://niyora.com/research/papers/effectiveness-of-pumpkin-seed-cucurbita-moschata-extract-in-reducing-2026/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does pumpkin seed extract reduce PMS symptoms in teenage girls? Randomised trial, 2026 # Does pumpkin seed extract reduce PMS symptoms in teenage girls? Yes. Taking 500 mg of pumpkin seed extract twice daily for 10 days significantly reduced PMS symptoms more than taking it once daily or placebo. Moderate study design 42 adolescent girls in Indonesia with PMS ## What they did RCT with 42 adolescent girls in Indonesia with PMS, randomly divided into three groups for 10 days. One group received pumpkin seed extract 500 mg twice daily, another received 500 mg once daily, and a control group received placebo tablets 500 mg once daily. ## What they found The group taking pumpkin seed extract 500 mg twice daily had the most significant symptom reduction with a mean score of 23.07 (p=0.000). ## What it means for you Pumpkin seed extract might work as a natural treatment for teenage PMS. However, this is a small study in one country and we don't know if it works the same in other groups of girls or populations. 42 adolescent girls studied 500mg 2x/day effective dose 10 days treatment duration ## About the study Original title Effectiveness of Pumpkin Seed (Cucurbita moschata) Extract in Reducing Premenstrual Syndrome Symptoms in Adolescent Girls Authors Eka Apriadi Farkhati Nafi’ah, Sri Sumarn, Sri Endang Windiarti Journal Journal Midwifery Jurusan Kebidanan Politeknik Kesehatan Gorontalo Year 2026 Study design Randomised trial Participants 42 What was tested Pumpkin seed extract 500 mg twice daily for 10 days Open access Yes Read the paper [doi.org/10.52365/jm.v12i1.1657](https://doi.org/10.52365/jm.v12i1.1657) Original abstract Premenstrual Syndrome (PMS) is a common condition among adolescent girls, characterized by physical and emotional complaints that can interfere with daily activities. In Indonesia, the prevalence of PMS is reported to reach approximately 85% among women of reproductive age, with 60–75% experiencing moderate to severe PMS. This study aimed to evaluate the effectiveness of pumpkin seed extract (Cucurbita moschata) in reducing PMS symptoms in adolescent girls. A quantitative approach was applied using a true experimental design with a pre-test and post-test control group design. The study population consisted of adolescent girls experiencing PMS in the Poltekkes Kemenkes Semarang area. A total of 42 respondents were selected using randomized clinical trial sampling and divided into three groups: intervention 1 (pumpkin seed extract 500 mg, twice daily), intervention 2 (500 mg, once daily), and a control group receiving 500 mg amylum tablets once daily for 10 days. The results showed that administration of pumpkin seed extract at a dose of 500 mg twice daily for 10 days produced the most significant reduction in PMS symptoms (p = 0.000; mean = 23.07). Pumpkin seed extract has potential as an effective natural therapy to alleviate PMS symptoms in adolescent girls. Reproduced under CC-BY-SA. ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2026 Does aerobic or resistance exercise reduce anxiety in women with PMS? Cohort study, 2025 How common is PMS in Chinese teenage girls, and what factors are linked to it? Systematic review, 2025 Does alcohol use affect menstrual health in teenage girls? Systematic review, 2025 Does teaching adolescent girls about their menstrual cycle and health help reduce period pain and PMS? Randomised trial, 2024 Does curcumin-piperine combination improve antioxidant activity in women with PMS and period pain? Systematic review, 2024 How common is premenstrual syndrome in Africa, and what factors increase the risk? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗