---
title: Does Jingqianshu granules, a Chinese herbal medicine, help PMS symptoms?
description: Yes, significantly more than placebo over three menstrual cycles, with no serious safety problems reported.
url: https://niyora.com/research/papers/efficacy-and-safety-of-jingqianshu-granules-in-patients-with-premenstrual-2025/
---

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- Does Jingqianshu granules, a Chinese herbal medicine, help PMS symptoms?

Randomised trial, 2025

# Does Jingqianshu granules, a Chinese herbal medicine, help PMS symptoms?

Yes, significantly more than placebo over three menstrual cycles, with no serious safety problems reported.

 Moderate study design

156 women with PMS (104 received treatment, 52 placebo)

## What they did

156 women were randomly assigned to take Jingqianshu granules (104 women) or placebo (52 women) for three menstrual cycles, then followed for three more cycles without treatment. Symptoms were tracked daily.

## What they found

After three treatment cycles, symptom scores (DRSP) dropped more in the treatment group than placebo. In the main analysis, scores fell by 14.3 ± 8.85 with granules versus 10.1 ± 7.61 with placebo. In the stricter analysis they fell by 14.5 ± 8.61 versus 10.2 ± 7.13. Both were statistically significant. No serious side effects were reported.

## What it means for you

Jingqianshu granules reduced PMS symptoms better than placebo and were safe. This is a useful treatment option for PMS. Limitation: Only studied in China, only tested for a specific type of PMS in Traditional Chinese Medicine terms, and not compared to standard treatments.

156

women randomized

-14.3 ± 8.85

symptom score reduction with granules

-10.1 ± 7.61

symptom score reduction with placebo

## About the study

Original title Efficacy and safety of Jingqianshu granules in patients with premenstrual syndrome: a multicenter, randomized, double-blind, placebo-controlled trial Authors Zhou Z, Li W, Liu Y et al. Journal International journal of clinical pharmacy Year 2025 Study design Randomised trial Participants 156 What was tested Jingqianshu granules (Chinese herbal medicine) versus placebo Read the paper [doi.org/10.1007/s11096-025-01949-5](https://doi.org/10.1007/s11096-025-01949-5)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)

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