--- title: Does rimegepant help prevent migraines that happen around your period? description: Yes, in this study rimegepant worked well. Women who took it around their period had fewer, shorter, and less severe migraines, and their quality of life impr url: https://niyora.com/research/papers/efficacy-and-safety-of-rimegepant-in-chinese-women-with-pure-menstrual-migraine-2026/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does rimegepant help prevent migraines that happen around your period? Study, 2026 # Does rimegepant help prevent migraines that happen around your period? Yes, in this study rimegepant worked well. Women who took it around their period had fewer, shorter, and less severe migraines, and their quality of life improved. However, this was a small study without a comparison group. Moderate study design 43 Chinese women with pure menstrual migraine, mean age 37 years ## What they did 43 Chinese women with menstrual migraines took 75 mg rimegepant every other day during the 5 to 6 days around their period (from 2 days before menstruation to 3 days after it started). They did this for 3 menstrual cycles. Researchers measured how long migraines lasted, how often they happened, how severe they were, and how much they affected daily activities. ## What they found After 3 cycles, attack duration decreased by 20.5 hours from baseline. Headache severity improved by 6 points. The number of perimenstrual headache days improved by 1.1 day. Quality of life scores improved by 11.4 points on one measure and 10.1 points on another. Only 2 women reported mild side effects. Anxiety, depression, and sleep quality did not improve. ## What it means for you Rimegepant taken around your period may help prevent menstrual migraines and improve quality of life. But the study was small and only included Chinese women, so we don't know if it works the same way for all women everywhere. There was no control group, so we can't be completely certain rimegepant caused the improvement rather than other factors. 20.5 hours attack duration decrease 6 points headache severity reduction 1.1 day perimenstrual headache days improvement ## About the study Original title Efficacy and safety of rimegepant in Chinese women with pure menstrual migraine: a retrospective observational study Authors Ye W, Fan Y, Liu J et al. Journal BMC neurology Year 2026 Study design Study Participants 43 What was tested 75 mg rimegepant every other day during perimenstrual period (from 2 days before to 3 days after menstruation start) Open access Yes Read the paper [doi.org/10.1186/s12883-026-04859-9](https://doi.org/10.1186/s12883-026-04859-9) ## Topics [Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Sleep and insomnia](https://niyora.com/research/topics/symptom-sleep/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/)[Migraine](https://niyora.com/research/topics/comorbidity-migraine/)[Quality of life and daily functioning](https://niyora.com/research/topics/life-area-quality-of-life/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Cohort study, 2025 What causes migraine in female college students who have PMS? Randomised trial, 2026 Does Kundalini Reiki help reduce PMS symptoms and improve quality of life? Randomised trial, 2026 Does a warm footbath help PMS symptoms and sleep quality? Cohort study, 2025 Do women with PMS or PMDD report lower quality of life than women without these conditions? Survey study, 2026 Are menstrual characteristics linked to depression and anxiety in teenage girls? Randomised trial, 2026 Does education about PMS symptoms help reduce pain and stress? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗