---
title: Does vitamin E reduce PMS symptoms? | Niyora
description: Yes, vitamin E significantly improved certain emotional and physical PMS symptoms compared to placebo. This was a moderate-sized randomized trial.
url: https://niyora.com/research/papers/efficacy-of-alpha-tocopherol-in-the-treatment-of-the-premenstrual-syndrome-1987/
---

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- Does vitamin E reduce PMS symptoms?

Randomised trial, 1987

# Does vitamin E reduce PMS symptoms?

Yes, vitamin E significantly improved certain emotional and physical PMS symptoms compared to placebo. This was a moderate-sized randomized trial.

 Moderate study design

46 women with PMS (41 completed the trial)

## What they did

A randomized, double-blind, placebo-controlled trial. Women with PMS took either 400 IU of vitamin E or placebo daily for 3 menstrual cycles and completed standardized PMS questionnaires before and after treatment.

## What they found

Of the 46 women enrolled, 41 completed the study. Women treated with vitamin E showed significant improvement in certain emotional and physical symptoms compared to placebo.

## What it means for you

Vitamin E may help certain PMS symptoms. The study does not specify which particular symptoms improved most or by how much, so larger studies would strengthen confidence in these results.

46

women enrolled

41

completed the trial

400 IU

daily dose

## About the study

Original title Efficacy of alpha-tocopherol in the treatment of the premenstrual syndrome Authors London RS, Murphy L, Kitlowski KE et al. Journal The Journal of reproductive medicine Year 1987 Study design Randomised trial Participants 46 What was tested 400 IU vitamin E daily for 3 cycles Read the paper [https://pubmed.ncbi.nlm.nih.gov/3302248/](https://pubmed.ncbi.nlm.nih.gov/3302248/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Vitamin E](https://niyora.com/research/topics/treatment-vitamin-e/)

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## Related studies

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Do vitamin D and E supplements reduce menstrual pain and PMS symptoms?

Cohort study, 2021

Are low antioxidant vitamins or high oxidative stress linked to premenstrual syndrome?

Systematic review, 2009

Which herbs, vitamins and minerals help treat PMS?

Randomised trial, 2000

Which dietary supplements help PMS?

Study, 2024

Does a combination of evening primrose oil, tocotrienol, and vitamin B6 reduce premenstrual symptoms?

Randomised trial, 2023

Does gamma-tocopherol (a form of vitamin E) reduce premenstrual syndrome symptoms?

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