--- title: Is diabetes linked to PMS, and could diabetes drugs affect it? description: This is a review of ideas, not a study with new data, so it cannot prove a link. It suggests diabetes and some diabetes drugs could plausibly worsen or trigge url: https://niyora.com/research/papers/emerging-perspectives-on-the-impact-of-diabetes-mellitus-and-anti-diabetic-drugs-2024/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Is diabetes linked to PMS, and could diabetes drugs affect it? Survey study, 2024 # Is diabetes linked to PMS, and could diabetes drugs affect it? This is a review of ideas, not a study with new data, so it cannot prove a link. It suggests diabetes and some diabetes drugs could plausibly worsen or trigger PMS-like symptoms, but this needs to be tested properly. Early or limited evidence Not a study of patients; a review of existing research on women with diabetes and PMS. ## What they did The authors wrote a narrative review, meaning they looked at existing research and theories about diabetes, anti-diabetic drugs, and PMS, and discussed how they might connect. No new patients were studied and no data was collected. ## What they found Hormones involved in PMS can also affect blood sugar control. People with diabetes are more prone to anxiety, depression, fatigue and difficulty concentrating, which overlap with PMS symptoms. Some diabetes drugs may cause side effects (low blood sugar with sulfonylureas, fluid retention with thiazolidinediones) that mimic PMS symptoms. Diabetes may also disrupt gut bacteria, reducing substances like short-chain fatty acids and serotonin that normally protect against PMS. ## What it means for you The idea that diabetes and certain diabetes drugs could worsen PMS is plausible but unproven. Because this is a review of existing theories rather than a clinical trial, it cannot tell us whether treating diabetes differently would actually help PMS symptoms. The authors say proper clinical trials are needed. ## About the study Original title Emerging Perspectives on the Impact of Diabetes Mellitus and Anti-Diabetic Drugs on Premenstrual Syndrome. A Narrative Review Authors Azmy Nabeh O, Amr A, Faoosa AM et al. Journal Diabetes therapy : research, treatment and education of diabetes and related disorders Year 2024 Study design Survey study What was tested None tested directly; the review discusses anti-diabetic drugs as a topic, not as a tested treatment. Open access Yes Read the paper [doi.org/10.1007/s13300-024-01585-8](https://doi.org/10.1007/s13300-024-01585-8) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[IBS and gut symptoms](https://niyora.com/research/topics/comorbidity-ibs-gi/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Case-control study, 2009 How common is irritable bowel syndrome in Korean teenage girls and what causes it? Survey study, 2024 How do hormonal changes during the menstrual cycle affect gut health and mood? Survey study, 2020 Do women with IBS and period problems have worse psychological symptoms? Randomised trial, 2026 Does Kundalini Reiki help reduce PMS symptoms and improve quality of life? Systematic review, 2026 Does vitamin D supplementation help PMS symptoms? Systematic review, 2026 Do mindfulness and relaxation techniques help with PMS symptoms? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗