---
title: Can a saliva test show menstrual stress? | Niyora
description: Possibly. The study found that levels of progesterone and amylase in saliva showed a relationship with menstrual distress and premenstrual symptoms, suggestin
url: https://niyora.com/research/papers/evaluation-of-stress-on-menstrual-cycle-using-salivary-amylase-activity-2012/
---

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- Can a saliva test show menstrual stress?

Survey study, 2012

# Can a saliva test show menstrual stress?

Possibly. The study found that levels of progesterone and amylase in saliva showed a relationship with menstrual distress and premenstrual symptoms, suggesting saliva tests might be useful for tracking menstrual stress.

 Early or limited evidence

28 healthy women, average age 33.4 years

## What they did

Researchers tested saliva from 28 women to measure their hormones and stress chemicals, and compared these to a questionnaire about menstrual symptoms.

## What they found

Progesterone levels in saliva after menstruation were related to distress reported during the premenstrual and menstrual phases. Saliva amylase (a measure of stress activity) during the night of the premenstrual phase was related to premenstrual, menstrual, and postmenstrual symptom scores.

## What it means for you

Saliva testing might be a non-invasive way to monitor menstrual stress in the future. The main limit is the small sample size (28 women), and this was just showing a relationship, not proving that saliva tests actually predict symptoms or help manage them.

28

women studied

33.4 years

average age of women

## About the study

Original title Evaluation of Stress on Menstrual Cycle Using Salivary Amylase Activity Authors Asami Nakagawa, Makoto SASAKI, Masaki Yamaguchi Journal Journal of Life Support Engineering Year 2012 Study design Survey study What was tested None Open access Yes Read the paper [doi.org/10.5136/lifesupport.24.123](https://doi.org/10.5136/lifesupport.24.123)

## Topics

[Stress](https://niyora.com/research/topics/symptom-stress/)

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