---
title: Can femicomfort (vitamin B6, E, and evening primrose oil) relieve PMS symptoms?
description: Yes. Women taking femicomfort reported relief of PMS symptoms compared to placebo. The supplement was well-tolerated with no significant increase in side effe
url: https://niyora.com/research/papers/femicomfort-in-the-treatment-of-premenstrual-syndromes-a-double-blind-randomized-2010/
---

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- Can femicomfort (vitamin B6, E, and evening primrose oil) relieve PMS symptoms?

Randomised trial, 2010

# Can femicomfort (vitamin B6, E, and evening primrose oil) relieve PMS symptoms?

Yes. Women taking femicomfort reported relief of PMS symptoms compared to placebo. The supplement was well-tolerated with no significant increase in side effects.

 Moderate study design

Women aged 20 to 45 with regular menstrual cycles and PMS for at least 6 months

## What they did

Double-blind randomized trial from November 2009 to April 2010. Women aged 20 to 45 with regular menstrual cycles and at least 6 months of PMS symptoms were randomly assigned to receive femicomfort capsules or placebo for 2 menstrual cycles. Symptoms were measured using a checklist of 17 premenstrual symptoms.

## What they found

Femicomfort was effective in relieving PMS symptoms compared to placebo. There was no significant difference in side effects between the femicomfort and placebo groups.

## What it means for you

The supplement may help reduce PMS. The abstract does not provide the specific numbers showing how much the symptoms improved in each group.

20-45

age range of women

2

menstrual cycles of treatment

17

symptoms measured

## About the study

Original title Femicomfort in the treatment of premenstrual syndromes: a double-blind, randomized and placebo controlled trial Authors Kashani L, Saedi N, Akhondzadeh S Journal Iranian journal of psychiatry Year 2010 Study design Randomised trial What was tested Femicomfort capsules containing vitamin B6, vitamin E, and evening primrose oil for 2 menstrual cycles Open access Yes Read the paper [https://pubmed.ncbi.nlm.nih.gov/22952490/](https://pubmed.ncbi.nlm.nih.gov/22952490/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Vitamin B6](https://niyora.com/research/topics/treatment-vitamin-b6/)[Vitamin E](https://niyora.com/research/topics/treatment-vitamin-e/)[Evening primrose oil](https://niyora.com/research/topics/treatment-evening-primrose/)

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