--- title: Does treating heavy periods with endometrial ablation help period pain and premenstrual mood symptoms? description: Yes. When women had endometrial ablation (a procedure that reduces menstrual bleeding), both period pain and premenstrual mood symptoms like irritability and url: https://niyora.com/research/papers/in-office-endometrial-ablation-and-clinical-correlation-of-reduced-menstrual-2009/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does treating heavy periods with endometrial ablation help period pain and premenstrual mood symptoms? Cohort study, 2009 # Does treating heavy periods with endometrial ablation help period pain and premenstrual mood symptoms? Yes. When women had endometrial ablation (a procedure that reduces menstrual bleeding), both period pain and premenstrual mood symptoms like irritability and depression improved over 3 and 6 months. Moderate study design 148 women with heavy menstrual bleeding, 134 completed follow-up ## What they did Prospective cohort study of 148 women with heavy menstrual bleeding who underwent Thermachoice III endometrial ablation (a procedure that burns the uterine lining) performed in an office under local anesthesia. They were followed at 3 and 6 months after the procedure. ## What they found At 3 and 6 months, 52% had no periods and 48% had lighter periods. Of 79 women who had period pain at baseline, pain improved at both 3 and 6 months (p<0.005). Premenstrual mood symptoms (agitation, irritability, and depression) also improved at both 3 and 6 months. ## What it means for you Reducing menstrual bleeding through this surgical procedure may help both period pain and premenstrual mood symptoms. However, endometrial ablation is a surgical procedure with risks. The study had no comparison group and did not compare it to other treatments. Specific numbers for mood improvement are not provided. This procedure is meant for heavy periods, not specifically for PMDD. 148 Women treated 52% Became amenorrheic 79 With period pain who improved ## About the study Original title In-office endometrial ablation and clinical correlation of reduced menstrual blood loss and effects on dysmenorrhea and premenstrual symptomatology Authors Chapa HO, Venegas G, Antonetti AG et al. Journal The Journal of reproductive medicine Year 2009 Study design Cohort study Participants 148 What was tested Thermachoice III endometrial ablation procedure Read the paper [https://pubmed.ncbi.nlm.nih.gov/19438165/](https://pubmed.ncbi.nlm.nih.gov/19438165/) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Cohort study, 2025 How common is PMS in Chinese teenage girls, and what factors are linked to it? Randomised trial, 2024 Does curcumin reduce depression, anxiety, and stress in women with PMS and dysmenorrhea? Systematic review, 2024 Does yoga help reduce PMS symptoms? Systematic review, 2021 Does damask rose help reduce menstrual pain, headache, fatigue, anxiety, and bloating? Survey study, 2026 Are menstrual characteristics linked to depression and anxiety in teenage girls? Survey study, 2026 Does exercise help college women with period problems and mental health? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗