---
title: Does the menstrual cycle phase affect a woman's ability to quit smoking?
description: Yes. Women had significantly higher premenstrual symptoms and smoking urges in the luteal phase, and variability in these measures was linked to relapse.
url: https://niyora.com/research/papers/influence-of-phase-related-variability-in-premenstrual-symptomatology-mood-2009/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Does the menstrual cycle phase affect a woman's ability to quit smoking?

Randomised trial, 2009

# Does the menstrual cycle phase affect a woman's ability to quit smoking?

Yes. Women had significantly higher premenstrual symptoms and smoking urges in the luteal phase, and variability in these measures was linked to relapse.

 Moderate study design

25 women intending to quit smoking

## What they did

25 women intending to quit smoking were monitored while smoking normally during their follicular and luteal phases. Researchers measured mood, premenstrual symptoms, smoking withdrawal, and how many cigarettes they smoked each day.

## What they found

Premenstrual symptoms and some mood and smoking withdrawal measures were significantly higher during the luteal phase than the follicular phase. Variability in these symptoms was associated with relapse. Cigarettes per day did not differ between phases.

## What it means for you

The menstrual cycle may affect smoking cessation success through hormone-related changes in symptoms and cravings. Main limit: small sample of 25 women.

25

women studied

luteal phase

phase with higher symptoms

p=0.0186

urge to smoke variability linked to relapse

## About the study

Original title Influence of phase-related variability in premenstrual symptomatology, mood, smoking withdrawal, and smoking behavior during ad libitum smoking, on smoking cessation outcome Authors Allen SS, Allen AM, Pomerleau CS Journal Addictive behaviors Year 2009 Study design Randomised trial Participants 25 What was tested Observation only - no intervention Open access Yes Read the paper [doi.org/10.1016/j.addbeh.2008.08.009](https://doi.org/10.1016/j.addbeh.2008.08.009)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Alcohol, smoking and substance use](https://niyora.com/research/topics/comorbidity-substance-use/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Survey study, 2025

Does PMDD or PMS affect quality of life?

Systematic review, 2025

Does alcohol use affect menstrual health in teenage girls?

Systematic review, 2021

Does substance use change across the menstrual cycle, especially in women with PMS or PMDD?

Cohort study, 2026

Are diet and lifestyle linked to premenstrual symptoms in college students?

Cohort study, 2026

Does cannabis use vary across the menstrual cycle in people with premenstrual disorders?

Survey study, 2024

Is physical activity linked to PMS symptoms?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗
