---
title: Can barley and chrysanthemum extract reduce PMS symptoms? | Niyora
description: In laboratory tests and mice, this extract reduced prolactin and inflammation markers, which could help PMS, but human studies have not been done. We cannot s
url: https://niyora.com/research/papers/lomens-p0-mixed-extracts-of-hordeum-vulgare-and-chrysanthemum-zawadskii-regulate-2021/
---

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- Can barley and chrysanthemum extract reduce PMS symptoms?

Survey study, 2021

# Can barley and chrysanthemum extract reduce PMS symptoms?

In laboratory tests and mice, this extract reduced prolactin and inflammation markers, which could help PMS, but human studies have not been done. We cannot say yet whether it works in women.

 Early or limited evidence

Laboratory cells and mice models (no human participants)

## What they did

Laboratory and animal study. Researchers tested barley extract, chrysanthemum extract, and their mixture (Lomens-P0) in cells and in mice with high prolactin levels. They measured prolactin secretion, inflammation markers, and hormone levels.

## What they found

Both extracts reduced prolactin secretion and inflammatory markers (IL-1β, IL-6, TNF-α, iNOS, COX-2) in laboratory cells (P < 0.01). In mice with high prolactin, Lomens-P0 suppressed prolactin secretion, normalized sex hormone balance, and significantly reduced inflammatory markers in uterine tissue. The active components were identified as tricin and chlorogenic acid.

## What it means for you

This natural mixture might help prevent or treat PMS by lowering prolactin and inflammation. However, these are only laboratory and animal findings. No human studies are presented. We do not know if the extract works in women or at what dose.

P < 0.01

reduction in inflammatory markers in lab cells

## About the study

Original title Lomens-P0 (mixed extracts of Hordeum vulgare and Chrysanthemum zawadskii ) regulate the expression of factors affecting premenstrual syndrome symptoms Authors Lee YS, Jeon H, Her YM et al. Journal Nutrition research and practice Year 2021 Study design Survey study What was tested Lomens-P0 extract (mixture of barley and chrysanthemum) Open access Yes Read the paper [doi.org/10.4162/nrp.2021.15.6.715](https://doi.org/10.4162/nrp.2021.15.6.715)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)

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