---
title: Do women with PMS have lower magnesium levels? | Niyora
description: Women with PMS have significantly lower magnesium inside their red blood cells compared to women without PMS, but magnesium in the liquid part of blood is nor
url: https://niyora.com/research/papers/magnesium-and-the-premenstrual-syndrome-1986/
---

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- Do women with PMS have lower magnesium levels?

Study, 1986

# Do women with PMS have lower magnesium levels?

Women with PMS have significantly lower magnesium inside their red blood cells compared to women without PMS, but magnesium in the liquid part of blood is normal. The practical importance of this finding is not yet clear.

 Early or limited evidence

105 women with premenstrual syndrome compared to women without PMS

## What they did

Researchers measured magnesium levels in 105 women with PMS in two places: in the liquid part of blood (plasma) and inside red blood cells (erythrocytes). They compared these measurements to magnesium levels in women without PMS.

## What they found

Women with PMS had significantly lower magnesium inside their red blood cells compared to women without PMS. The magnesium in the liquid part of blood was the same in both groups.

## What it means for you

There may be a magnesium deficiency inside the cells of women with PMS, but it does not show up in standard blood tests. The practical importance of this cellular deficiency is not yet known.

105

women with PMS studied

## About the study

Original title Magnesium and the premenstrual syndrome Authors Sherwood RA, Rocks BF, Stewart A et al. Journal Annals of clinical biochemistry Year 1986 Study design Study Participants 105 What was tested No intervention; comparison study Read the paper [doi.org/10.1177/000456328602300607](https://doi.org/10.1177/000456328602300607)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Magnesium](https://niyora.com/research/topics/treatment-magnesium/)

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