---
title: How do women with PMS differ from those without PMS on mental health?
description: Women with PMS had higher depression and stress than community women without it. Some women without a PMS diagnosis showed cyclical symptom patterns, suggesti
url: https://niyora.com/research/papers/menstrual-cycle-symptoms-comparison-of-a-non-clinical-sample-with-a-patient-1988/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- How do women with PMS differ from those without PMS on mental health?

Survey study, 1988

# How do women with PMS differ from those without PMS on mental health?

Women with PMS had higher depression and stress than community women without it. Some women without a PMS diagnosis showed cyclical symptom patterns, suggesting they may develop PMS later.

 Early or limited evidence

32 community women and 75 women with diagnosed PMS

## What they did

Researchers compared 32 community women without PMS to 75 with diagnosed PMS. They gave tests measuring depression, anxiety, stress, and self-esteem. Menstrual symptoms were rated at follicular phase (days 6-8) and premenstrual phase (days 26-28) over two cycles. Urine hormone levels were measured. The women were divided into 13 with pronounced cyclical symptoms and 19 with minimal changes.

## What they found

Women with PMS had higher depression, stress, and lower self-esteem than community women. The 13 community women with pronounced cyclical symptoms were identified as an "at-risk" group for developing PMS.

## What it means for you

Women with PMS appear to have more depression and stress than those without it. Some women without a diagnosis may be at future risk. The main limit is the small sample and cross-sectional design, which shows correlation but not cause and effect.

32

community women without diagnosed PMS

75

women with diagnosed PMS

13

community women with pronounced cyclical symptoms

## About the study

Original title Menstrual cycle symptoms: comparison of a non-clinical sample with a patient group Authors Morse CA, Dennerstein L, Varnavides K et al. Journal Journal of affective disorders Year 1988 Study design Survey study Participants 75 What was tested None; this was a comparison study. Read the paper [doi.org/10.1016/0165-0327(88)90070-5](https://doi.org/10.1016/0165-0327(88)90070-5)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Stress](https://niyora.com/research/topics/symptom-stress/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)[Pregnancy and postpartum](https://niyora.com/research/topics/comorbidity-postpartum/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Cohort study, 1991

What causes postpartum blues (mood changes in the week after giving birth)?

Non-randomised trial, 2024

Does luteal phase sertraline treatment affect stress hormones and inflammation in PMDD?

Review, 2004

Could a brain hormone called allopregnanolone explain mood problems like PMDD in women?

Review, 2023

What treatments help mental and physical health problems linked to the menstrual cycle?

Systematic review, 2022

What increases the risk of depression after childbirth?

Systematic review, 2021

Are there hormone changes that could explain PMDD or depression in women?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗
