---
title: Does norethisterone enantate, an injectable contraceptive, help PMS?
description: Yes, though the study is very small. Women on norethisterone enantate had significantly fewer and less severe symptoms compared to women on oral contraceptive
url: https://niyora.com/research/papers/norethisterone-enantate-in-the-treatment-of-premenstrual-syndrome-1995/
---

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- Does norethisterone enantate, an injectable contraceptive, help PMS?

Cohort study, 1995

# Does norethisterone enantate, an injectable contraceptive, help PMS?

Yes, though the study is very small. Women on norethisterone enantate had significantly fewer and less severe symptoms compared to women on oral contraceptive pills.

 Early or limited evidence

20 women with severe PMS who required effective contraception

## What they did

20 women with severe PMS who needed contraception compared their premenstrual symptom scores on norethisterone enantate versus oral contraceptive pills in a prospective study.

## What they found

Significantly fewer and less severe symptoms were experienced on norethisterone enantate than on oral contraceptives.

## What it means for you

This injectable contraceptive may control PMS better than birth control pills. Limitation: only 20 women studied. Compared two hormonal treatments with no non-hormonal control group.

20

women studied

## About the study

Original title Norethisterone enantate in the treatment of premenstrual syndrome Authors Gunston KD Journal South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Year 1995 Study design Cohort study Participants 20 What was tested Norethisterone enantate compared to oral contraceptives Read the paper [https://pubmed.ncbi.nlm.nih.gov/8545742/](https://pubmed.ncbi.nlm.nih.gov/8545742/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)

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