---
title: What medications work best for PMDD? | Niyora
description: The abstract does not include findings or results, so no conclusion can be drawn from it.
url: https://niyora.com/research/papers/pharmacotherapy-for-premenstrual-dysphoric-disorder-a-meta-analysis-of-phase-3-2012/
---

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- What medications work best for PMDD?

Systematic review, 2012

# What medications work best for PMDD?

The abstract does not include findings or results, so no conclusion can be drawn from it.

 Strong study design

Women with PMDD of reproductive age (3-8% of this population).

## What they did

Meta-analysis of phase 3 clinical trials examining pharmacotherapy (medication treatment) for PMDD.

## What they found

The abstract is incomplete and does not present results or findings.

## What it means for you

Unable to determine from this abstract. The full paper would need to be reviewed to understand which medications the authors recommend for PMDD.

3-8%

Percentage of reproductive-age women with PMDD

80%

Women experiencing some premenstrual physical or emotional changes

150

Reported premenstrual symptoms

## About the study

Original title Pharmacotherapy for premenstrual dysphoric disorder: A meta-analysis of phase 3 trials Authors Sun Kyoung Yum, Min Ji Ryu, Nayoon Park et al. Journal Korean Journal of Obstetrics & Gynecology Year 2012 Study design Systematic review What was tested Medications for PMDD, commonly oral contraceptives and antidepressants. Open access Yes Read the paper [doi.org/10.5468/kjog.2012.55.3.143](https://doi.org/10.5468/kjog.2012.55.3.143)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Bloating, breast tenderness and physical symptoms](https://niyora.com/research/topics/symptom-physical-symptoms/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

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Review, 2015

What do we know about PMS and PMDD and how are they treated?

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