---
title: How can doctors manage premenstrual-like symptoms caused by hormonal treatments containing progestogen?
description: No clear evidence exists, but doctors should recognize that hormonal treatments like contraception can cause PMS-like symptoms cycling with medication use, te
url: https://niyora.com/research/papers/potential-strategies-to-avoid-progestogen-induced-premenstrual-disorders-2012/
---

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- How can doctors manage premenstrual-like symptoms caused by hormonal treatments containing progestogen?

Review, 2012

# How can doctors manage premenstrual-like symptoms caused by hormonal treatments containing progestogen?

No clear evidence exists, but doctors should recognize that hormonal treatments like contraception can cause PMS-like symptoms cycling with medication use, termed progestogen-induced premenstrual disorder, and manage based on clinical experience.

 Early or limited evidence

Not applicable. This is a review article, not a study of people.

## What they did

Review article discussing strategies to prevent or manage premenstrual-like symptoms caused by hormonal therapies. The authors examined how various progestogen-containing treatments can introduce or worsen PMS symptoms and reviewed approaches based on clinical experience since research evidence is lacking.

## What they found

PMS-like symptoms can be introduced or reintroduced during hormonal treatments including combined oral contraception, progestogen-only contraception, progestogen therapy for heavy periods or endometriosis, sequential hormone replacement therapy, and other strategies requiring endometrial protection. When symptoms cycle in pattern similar to PMS, the condition is termed progestogen-induced premenstrual disorder. Nearly all current clinical practice in managing this depends on clinician experience rather than research evidence.

## What it means for you

Women taking hormonal treatments should be aware that PMS-like symptoms might actually be caused by the medication, particularly progestogen. Doctors often miss this connection. Management relies on clinical experience rather than research evidence. Progestogen should be considered as a potential cause when evaluating women on hormonal therapies.

progestogen

medication component often causing PMS-like symptoms

multiple types

hormonal therapies with this problem

unclear

best approach to managing these symptoms

## About the study

Original title Potential strategies to avoid progestogen-induced premenstrual disorders Authors Baker LJ, O'Brien PM Journal Menopause international Year 2012 Study design Review What was tested Not applicable Read the paper [doi.org/10.1258/mi.2012.012016](https://doi.org/10.1258/mi.2012.012016)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[GnRH agonists and ovarian suppression](https://niyora.com/research/topics/treatment-gnrh/)[Estradiol, progesterone and hormone therapy](https://niyora.com/research/topics/treatment-hormone-therapy/)[Surgical menopause](https://niyora.com/research/topics/treatment-surgery/)[Endometriosis](https://niyora.com/research/topics/comorbidity-endometriosis/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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