---
title: Is your immune system response linked to asthma that gets worse before your period?
description: Yes. Women with asthma worsening before their period had higher levels of one immune marker (IgE) than those without. Specific allergens did not seem to matte
url: https://niyora.com/research/papers/premenstrual-asthma-and-atopy-markers-2010/
---

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- Is your immune system response linked to asthma that gets worse before your period?

Survey study, 2010

# Is your immune system response linked to asthma that gets worse before your period?

Yes. Women with asthma worsening before their period had higher levels of one immune marker (IgE) than those without. Specific allergens did not seem to matter.

 Early or limited evidence

59 asthmatic women of reproductive age

## What they did

59 asthmatic women tracked their breathing throughout their menstrual cycle and had blood tests for immune markers. Doctors graded asthma severity.

## What they found

31 of 59 women had asthma worsening before their period. Of those, 26 had high IgE levels, compared with 12 of the 28 without this pattern. 21 of the 31 tested positive for airborne allergens, versus 14 of the 28.

## What it means for you

Immune markers are more common in women whose asthma worsens before their period, suggesting immune activity plays a role in this pattern. The study was small, so findings need confirmation in larger research.

31 of 59

had asthma that worsened before their period

84%

with premenstrual asthma had high IgE

43%

without premenstrual asthma had high IgE

## About the study

Original title Premenstrual asthma and atopy markers Authors Pereira-Vega A, Sánchez JL, Maldonado JA et al. Journal Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology Year 2010 Study design Survey study Participants 59 What was tested None Read the paper [doi.org/10.1016/j.anai.2010.06.022](https://doi.org/10.1016/j.anai.2010.06.022)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual exacerbation (PME)](https://niyora.com/research/topics/condition-pme/)[Work and productivity](https://niyora.com/research/topics/life-area-work/)

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