---
title: What are premenstrual disorders and how should they be treated?
description: Premenstrual disorders are common and can be as disabling as major depression, but they are often under-recognized and poorly treated. Women with severe forms
url: https://niyora.com/research/papers/premenstrual-disorders-and-pmdd-a-review-2024/
---

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- What are premenstrual disorders and how should they be treated?

Review, 2024

# What are premenstrual disorders and how should they be treated?

Premenstrual disorders are common and can be as disabling as major depression, but they are often under-recognized and poorly treated. Women with severe forms need multidisciplinary care.

 Early or limited evidence

Reviews clinical literature on premenstrual disorders and PMDD

## What they did

A review providing clarity on diagnosis and management of premenstrual disorders, with a framework for non-specialists and emphasis on multidisciplinary team care for severe cases.

## What they found

PMDD, the severe form of premenstrual disorder, has a functional impact similar to major depression but remains under-recognized and poorly treated.

## What it means for you

Women with premenstrual disorders, especially PMDD, need better recognition and should receive care from multiple types of healthcare providers. This is a review summarizing existing knowledge rather than providing new research evidence.

## About the study

Original title Premenstrual disorders and PMDD - a review Authors Cary E, Simpson P Journal Best practice & research. Clinical endocrinology & metabolism Year 2024 Study design Review What was tested None. This is a literature review discussing management approaches. Open access Yes Read the paper [doi.org/10.1016/j.beem.2023.101858](https://doi.org/10.1016/j.beem.2023.101858)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Neurosteroids (allopregnanolone)](https://niyora.com/research/topics/treatment-neurosteroids/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Systematic review, 2021

Are there hormone changes that could explain PMDD or depression in women?

Study, 2026

What treatments work for PMDD?

Randomised trial, 2006

Do women with PMDD and depression process progesterone differently than others?

Non-randomised trial, 2024

Does luteal phase sertraline treatment affect stress hormones and inflammation in PMDD?

Study, 2008

How common is PMDD and how does it affect women's lives?

Review, 2004

Could a brain hormone called allopregnanolone explain mood problems like PMDD in women?

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