--- title: How many women with PMS want to participate in research studies? description: Very few. Only 10% of women with current PMS symptoms agreed to participate, and only 22% of those who started confirmed their diagnosis by keeping daily symp url: https://niyora.com/research/papers/premenstrual-disorders-bridging-research-and-clinical-reality-2003/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - How many women with PMS want to participate in research studies? Non-randomised trial, 2003 # How many women with PMS want to participate in research studies? Very few. Only 10% of women with current PMS symptoms agreed to participate, and only 22% of those who started confirmed their diagnosis by keeping daily symptom charts. Early or limited evidence 426 women with PMS from 6 primary care gynecology offices (out of 904 screened) ## What they did Open trial in 6 primary care gynecology offices. Researchers screened 904 women for PMS symptoms, tracked who participated and why, and looked for coexisting mental health conditions. ## What they found 47% of screened women (n=426) had current PMS symptoms. Of these, 41% were not interested in research, 36% were ineligible (symptoms not severe enough or other reasons), 10% agreed to keep daily symptom charts, and only 9 women (22% of those who charted) confirmed their symptoms. Among the 426 with PMS: 22% had depression, 5.4% had minor depression, and 14% had panic disorder. Among women with possible PMDD, 24% had suicidal thoughts and 20% had these thoughts for several days. ## What it means for you Many women in primary care have PMS and other mental health conditions together. Most don't want to participate in research. This means research trial results may not apply to typical patients. This was an open trial with no control group, so we cannot measure treatment effectiveness. 47% Women with PMS symptoms among those screened 10% Percentage who agreed to participate 22% Percentage of participants who confirmed PMS diagnosis ## About the study Original title Premenstrual disorders: bridging research and clinical reality Authors Yonkers KA, Pearlstein T, Rosenheck RA Journal Archives of women's mental health Year 2003 Study design Non-randomised trial Participants 426 What was tested Serotonin reuptake inhibitor medication Read the paper [doi.org/10.1007/s00737-003-0026-4](https://doi.org/10.1007/s00737-003-0026-4) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)[Anxiety disorders and OCD](https://niyora.com/research/topics/comorbidity-anxiety-disorders/)[Diagnosis experience and healthcare access](https://niyora.com/research/topics/life-area-healthcare-access/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Review, 2004 How should doctors diagnose and treat PMS and PMDD? Study, 2026 Do anxiety and depression get worse before your period if you already have a mental health condition? Cohort study, 2012 How quickly does fluoxetine start working for PMDD symptoms? Randomised trial, 2004 Does paroxetine controlled-release help PMDD symptoms? Randomised trial, 2002 Does myo-inositol help reduce PMDD symptoms? Review, 2001 What is the best treatment for depression and anxiety disorders, including PMDD? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗