---
title: Does tokito, a Japanese herbal medicine, relieve PMS and period pain?
description: A 46-year-old woman who had suffered for decades with PMS symptoms and severe period pain that did not respond to pain medication experienced complete relief
url: https://niyora.com/research/papers/premenstrual-syndrome-and-dysmenorrhea-successfully-managed-with-the-japanese-2021/
---

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- Does tokito, a Japanese herbal medicine, relieve PMS and period pain?

Case report, 2021

# Does tokito, a Japanese herbal medicine, relieve PMS and period pain?

A 46-year-old woman who had suffered for decades with PMS symptoms and severe period pain that did not respond to pain medication experienced complete relief after taking tokito, a Kampo (Japanese traditional medicine) formula. However, this is based on just one case.

 Early or limited evidence

One 46-year-old woman with decades-long PMS and severe period pain

## What they did

A 46-year-old woman with decades of premenstrual constipation, bloating, and cramping pain, as well as severe period pain that did not respond to nonsteroidal anti-inflammatory pain medication, was treated with tokito, a Kampo formula containing 10 herbs.

## What they found

All her PMS symptoms and period pain resolved without side effects.

## What it means for you

This shows one woman's response to the herbal medicine, but because it is just one case with no control group, we cannot be sure how well it would work for others or how long the relief lasts.

46

age in years

10

herbs in tokito formula

decades

duration of symptoms before treatment

## About the study

Original title Premenstrual syndrome and dysmenorrhea successfully managed with the Japanese traditional medicine tokito : A case report and literature review Authors Shiho Fukai‐Watabe, Satoru Ishibashi, Tokumu Watabe et al. Journal Traditional & Kampo Medicine Year 2021 Study design Case report What was tested Tokito, a Kampo herbal formula with 10 herbs Read the paper [doi.org/10.1002/tkm2.1304](https://doi.org/10.1002/tkm2.1304)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

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Systematic review, 2019

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Cohort study, 2018

Do women with PMS or period pain use more complementary therapies like vitamins or yoga over time?

Survey study, 2016

How do women use complementary and alternative medicine for menstrual pain?

Cohort study, 2016

How many Australian women have PMS and do they use complementary medicine?

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