---
title: Can the herbal supplement Agnus castus ease PMS symptoms in teenage girls?
description: In this small study, three months of Agnus castus (20mg daily) reduced most PMS symptoms in teenage girls, working best on mood-related and fluid-retention sy
url: https://niyora.com/research/papers/premenstrual-syndrome-clinical-manifestations-peculiarities-in-adolescents-2022/
---

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- Can the herbal supplement Agnus castus ease PMS symptoms in teenage girls?

Cohort study, 2022

# Can the herbal supplement Agnus castus ease PMS symptoms in teenage girls?

In this small study, three months of Agnus castus (20mg daily) reduced most PMS symptoms in teenage girls, working best on mood-related and fluid-retention symptoms and less well on skin and joint symptoms.

 Early or limited evidence

31 girls aged 17 to 19 with PMS

## What they did

31 girls aged 17 to 19 with PMS were followed before and during 3 months of treatment with Prefemin (Agnus castus 20mg). Symptoms were tracked using a questionnaire covering 47 PMS symptoms grouped into 6 categories.

## What they found

On average each girl had 13.1 PMS symptoms before treatment. Mood-related symptoms affected 100% of girls and improved in 71% with treatment, and fluid-retention symptoms also improved in 71%. Joint and muscle symptoms were common (77.4% of girls) but improved less often (58.1%). Skin symptoms affected 54.8% (17 girls), and about half of those girls (8) improved, with acne remaining a problem.

## What it means for you

Agnus castus may help with many PMS symptoms, especially mood and fluid-retention ones, and could be an alternative to other PMS medications, but it seemed less helpful for skin problems. The study was small and had no comparison group.

13.1

Average symptoms per girl before treatment

71%

Mood symptoms improved

58.1%

Joint/muscle symptoms improved

## About the study

Original title Premenstrual Syndrome Clinical Manifestations Peculiarities in Adolescents Authors Г.Н. Алимбаева, Т.Ю. Нурбаева Journal Репродуктивное здоровье Восточная Европа Year 2022 Study design Cohort study Participants 31 What was tested Agnus castus (Prefemin), 20mg daily for 3 months Open access Yes Read the paper [doi.org/10.34883/pi.2022.12.3.004](https://doi.org/10.34883/pi.2022.12.3.004)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Vitex agnus-castus (chasteberry)](https://niyora.com/research/topics/treatment-vitex/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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