---
title: Do SSRI antidepressants help treat premenstrual syndrome? | Niyora
description: A literature review suggests SSRIs could be an alternative treatment for PMS alongside traditional hormone therapy. However, this review does not provide spec
url: https://niyora.com/research/papers/premenstrual-syndrome-treatment-with-serotonin-uptake-inhibitor-antidepressants-2001/
---

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- Do SSRI antidepressants help treat premenstrual syndrome?

Review, 2001

# Do SSRI antidepressants help treat premenstrual syndrome?

A literature review suggests SSRIs could be an alternative treatment for PMS alongside traditional hormone therapy. However, this review does not provide specific evidence or results.

 Early or limited evidence

Women with premenstrual syndrome

## What they did

This was a literature review examining selective serotonin reuptake inhibitors (SSRIs), a type of antidepressant, for treating PMS.

## What they found

The review concluded that antidepressant treatment is becoming an alternative to traditional hormonal therapy for PMS. The abstract does not provide specific findings, results, or numbers from individual studies.

## What it means for you

SSRIs may help some women with PMS, but this is just a summary of what has been published. Without specific data on how many women improved or by how much, it is hard to know how well they work. More detailed information from the actual studies would be helpful.

## About the study

Original title [Premenstrual syndrome - treatment with serotonin uptake inhibitor antidepressants] Authors Trzebiatowska IA, Zwaliński M, Emerich J et al. Journal Ginekologia polska Year 2001 Study design Review What was tested Selective serotonin reuptake inhibitors (SSRIs) Read the paper [https://pubmed.ncbi.nlm.nih.gov/11757488/](https://pubmed.ncbi.nlm.nih.gov/11757488/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

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Survey study, 2011

Is premenstrual syndrome related to major depression?

Randomised trial, 2004

Does dosing sertraline continuously or just before the period work better for severe PMS?

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What medications work for PMDD when taken only during the second half of the menstrual cycle?

Review, 2004

How should doctors diagnose and treat PMS and PMDD?

Randomised trial, 2000

How should PMDD be diagnosed and treated?

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