---
title: Are prolactin levels different in women with PMS compared to women without?
description: No. Prolactin levels were the same in both groups and did not change throughout the menstrual cycle.
url: https://niyora.com/research/papers/prolactin-levels-in-the-premenstrual-syndrome-1982/
---

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- Are prolactin levels different in women with PMS compared to women without?

Case-control study, 1982

# Are prolactin levels different in women with PMS compared to women without?

No. Prolactin levels were the same in both groups and did not change throughout the menstrual cycle.

 Early or limited evidence

18 women with PMS, 10 control women

## What they did

Case-control study measuring prolactin in 18 women with PMS and 10 control women throughout their menstrual cycle.

## What they found

In the 18 women with PMS and 10 control women, there were no consistent prolactin changes during the cycle, no differences between groups, and no link between prolactin and mood changes.

## What it means for you

Prolactin does not appear to be involved in PMS. However, this was a small study testing only one hormone, so other hormones may still play a role.

18

women with PMS

10

control women

## About the study

Original title Prolactin levels in the premenstrual syndrome Authors O'Brien PM, Symonds EM Journal British journal of obstetrics and gynaecology Year 1982 Study design Case-control study Participants 18 Read the paper [doi.org/10.1111/j.1471-0528.1982.tb04701.x](https://doi.org/10.1111/j.1471-0528.1982.tb04701.x)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)

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