---
title: Do women with PMS have weaker bones due to calcium deficiency?
description: Yes. Women with PMS have lower bone density in the spine and hip compared to women without PMS, and they also have lower vitamin D levels.
url: https://niyora.com/research/papers/reduced-bone-mass-in-women-with-premenstrual-syndrome-1995/
---

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- Do women with PMS have weaker bones due to calcium deficiency?

Case-control study, 1995

# Do women with PMS have weaker bones due to calcium deficiency?

Yes. Women with PMS have lower bone density in the spine and hip compared to women without PMS, and they also have lower vitamin D levels.

 Moderate study design

Women with established PMS compared to asymptomatic controls, matched for age, race, body weight, and physical activity.

## What they did

Comparison study of women with PMS and asymptomatic controls matched for age, race, body weight, and physical activity. Bone density was measured at the spine and hip using dual-photon absorptiometry. Hormone levels related to calcium were measured during the luteal phase.

## What they found

Women with PMS had significantly lower bone density at the spine (1.18 versus 1.28 g/cm2) and in Ward's triangle at the hip (0.84 versus 0.91 g/cm2). They also had lower vitamin D levels (19.5 versus 25.3 ng/mL). There were no differences in other hormones or dietary calcium intake between groups.

## What it means for you

Women with PMS may have weaker bones and lower vitamin D, which could affect long-term bone health. However, the study found no difference in how much calcium women eat, so the cause is still unknown. This is a relatively small comparison study.

1.18 vs 1.28

spine bone density g/cm2 (PMS vs controls)

0.84 vs 0.91

hip bone density g/cm2 (PMS vs controls)

19.5 vs 25.3

vitamin D ng/mL (PMS vs controls)

## About the study

Original title Reduced Bone Mass in Women With Premenstrual Syndrome Authors Susan Thys‐Jacobs, Marsha Silverton, José Alvir et al. Journal Journal of Women s Health Year 1995 Study design Case-control study What was tested None - this was a comparison of existing groups Read the paper [doi.org/10.1089/jwh.1995.4.161](https://doi.org/10.1089/jwh.1995.4.161)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Cognition, concentration and memory](https://niyora.com/research/topics/symptom-cognition/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Calcium](https://niyora.com/research/topics/treatment-calcium/)

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