---
title: How much quality of life do women with untreated PMDD lose over their lifetime?
description: Untreated PMDD causes an expected loss of about 3 years of quality-adjusted life over a woman's lifetime, accounting for pregnancy and menstruation-free perio
url: https://niyora.com/research/papers/reduction-of-quality-adjusted-life-years-qalys-in-patients-with-premenstrual-2017/
---

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- How much quality of life do women with untreated PMDD lose over their lifetime?

Survey study, 2017

# How much quality of life do women with untreated PMDD lose over their lifetime?

Untreated PMDD causes an expected loss of about 3 years of quality-adjusted life over a woman's lifetime, accounting for pregnancy and menstruation-free periods. This is based on a preliminary survey of 66 untreated women.

 Early or limited evidence

66 untreated women with PMDD

## What they did

Cross-sectional study of 66 untreated women with PMDD. Researchers collected data on symptoms and quality of life during the menstrual cycle using the EQ-5D scale.

## What they found

The 66 women had a mean EQ-5D score of 0.795. Their expected loss of quality of life was about 0.14 years per year if PMDD is untreated. Over a lifetime, accounting for menopause and periods without menstruation, women with untreated PMDD are expected to experience about 3 years of lost quality of life.

## What it means for you

PMDD has a large impact on daily life and overall well-being. The main limits are that this is a preliminary survey of only 66 women with untreated PMDD, and it is cross-sectional.

66

women studied

0.14

years of quality of life lost per year

3

estimated lifetime years of lost quality of life

## About the study

Original title Reduction of quality-adjusted life years (QALYs) in patients with premenstrual dysphoric disorder (PMDD) Authors Yamada K, Kamagata E Journal Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation Year 2017 Study design Survey study Participants 66 What was tested None, observational study Read the paper [doi.org/10.1007/s11136-017-1642-1](https://doi.org/10.1007/s11136-017-1642-1)

## Topics

[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Quality of life and daily functioning](https://niyora.com/research/topics/life-area-quality-of-life/)

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