--- title: Is metabolic syndrome linked to worse PMS symptoms? | Niyora description: Women with metabolic syndrome had significantly more severe PMS symptoms than those without it. However, we cannot be sure if metabolic syndrome causes the se url: https://niyora.com/research/papers/relation-between-metabolic-syndrome-and-psychiatric-symptoms-severity-in-women-2024/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Is metabolic syndrome linked to worse PMS symptoms? Survey study, 2024 # Is metabolic syndrome linked to worse PMS symptoms? Women with metabolic syndrome had significantly more severe PMS symptoms than those without it. However, we cannot be sure if metabolic syndrome causes the severity or if they are simply linked. Early or limited evidence 300 women with PMS (150 with metabolic syndrome and 150 without) ## What they did Researchers compared 150 women with PMS and metabolic syndrome to 150 women with PMS but without metabolic syndrome, using standard diagnostic tools for both conditions. ## What they found Among women with metabolic syndrome, 35.3% had moderate-to-severe PMS, compared to 20.7% of those without metabolic syndrome. Women with metabolic syndrome had higher average weight (BMI 30.5 versus 25.2 kg/m2) and longer symptom duration (4.4 days versus 3.3 days). ## What it means for you Metabolic syndrome may be linked to worse PMS symptoms. However, this was a snapshot study of women who already had PMS, so we cannot determine cause and effect. The findings may not apply to all women with PMS. 35.3% vs 20.7% Moderate-to-severe PMS prevalence 30.5 vs 25.2 Average BMI (kg/m2) 4.4 vs 3.3 days Average symptom duration ## About the study Original title Relation between metabolic syndrome and psychiatric symptoms severity in women with premenstrual syndrome Authors Mohamed Basiouny Yahia, Medhat Ali Salah, Seham Sabry et al. Journal The Egyptian Journal of Neurology Psychiatry and Neurosurgery Year 2024 Study design Survey study Participants 300 What was tested None - this was an observational comparison Open access Yes Read the paper [doi.org/10.1186/s41983-024-00798-9](https://doi.org/10.1186/s41983-024-00798-9) Original abstract Abstract Background Premenstrual syndrome (PMS) is a clinical condition characterized by recurrent moderate-to-severe affective, physical, and behavioral symptoms during the menstrual cycle. The present study aimed to assess the relation between metabolic syndrome (MetS) and symptoms severity in patients with premenstrual syndrome (PMS). This multicentric propensity score matched analysis included 300 women with PMS. They comprised 150 women with MetS and 150 women without MetS. Diagnosis of PMS was based on the validated Arabic version of Premenstrual Symptoms Screening Tool (PSST). For the diagnosis of MetS, we adopted the Harmonized Joint Scientific Statement (HJSS) on metabolic syndrome recommendations. Results The present study included 300 patients with PMS. They comprised 150 patients with MetS and 150 patients without MetS. Comparison between the studied groups regarding the demographic and clinical data showed that patients with MetS had significantly higher BMI (30.5 ± 3.0 versus 25.2 ± 3.5 kg/m2, p < 0.001) and longer symptoms duration (4.4 ± 0.9 versus 3.3 ± 1.1 days, p < 0.001). Patients with MetS included higher frequency of moderate-to-severe PMS (35.3% versus 20.7%, p = 0.005). In patients with MetS, it was found that patients with moderate-to-severe PMS have significantly higher BMI, younger age at menarche and longer symptoms duration. Multivariate logistic regression analysis identified age at menarche [OR (95% CI): 0.7 (0.55–0.9), p = 0.005], PMS symptoms duration [OR (95% CI): 4.45 (3.0–6.6), p < 0.001] and MetS [OR (95% CI): 1.67 (1.34–2.53), p = 0.017] as significant predictors of moderate-to-severe PMS. Conclusions MetS is related to symptoms severity in PMS patients. Reproduced under CC-BY. ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2026 Does aerobic or resistance exercise reduce anxiety in women with PMS? Cohort study, 2025 How common is PMS in Chinese teenage girls, and what factors are linked to it? Systematic review, 2025 Does alcohol use affect menstrual health in teenage girls? Lab study, 2026 Do core stability exercises help women with PMDD? Study, 2026 What coping strategies help women manage PMS symptoms? Survey study, 2026 Is worry about climate change linked to worse PMS symptoms? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗