---
title: Can depression screening after birth predict who will develop PMS?
description: A high depression score after birth may signal increased risk of developing PMS or PMDD in the next year, but the evidence is preliminary and the difference w
url: https://niyora.com/research/papers/relationship-between-a-high-edinburgh-postnatal-depression-scale-score-and-2020/
---

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- Can depression screening after birth predict who will develop PMS?

Cohort study, 2020

# Can depression screening after birth predict who will develop PMS?

A high depression score after birth may signal increased risk of developing PMS or PMDD in the next year, but the evidence is preliminary and the difference was not statistically significant.

 Early or limited evidence

200 Japanese pregnant women, 178 without prior severe PMS or PMDD

## What they did

Researchers enrolled 200 Japanese pregnant women at 35-36 weeks of pregnancy. One month after delivery, they gave women a depression screening test (EPDS). They then tracked which women developed severe PMS or PMDD by 1 year after delivery.

## What they found

Of 178 women without severe PMS or PMDD before pregnancy, 19.0% (4 of 21) of those with high depression scores and 5.6% (5 of 89) of those with low depression scores developed severe PMS or PMDD within the year. The difference was not statistically significant (p equals 0.07).

## What it means for you

Women with high depression scores after birth may be more likely to develop PMS or PMDD later, but this study was small and the finding was not statistically significant. Much larger studies are needed to confirm this relationship.

19.0%

High depression group with PMS/PMDD (4 of 21)

5.6%

Low depression group with PMS/PMDD (5 of 89)

0.07

p-value for group difference

## About the study

Original title Relationship between a high Edinburgh Postnatal Depression Scale score and premenstrual syndrome: A prospective, observational study Authors Takayama E, Tanaka H, Kamimoto Y et al. Journal Taiwanese journal of obstetrics & gynecology Year 2020 Study design Cohort study Participants 200 What was tested None Open access Yes Read the paper [doi.org/10.1016/j.tjog.2020.03.003](https://doi.org/10.1016/j.tjog.2020.03.003)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Pregnancy and postpartum](https://niyora.com/research/topics/comorbidity-postpartum/)[Relationships and partners](https://niyora.com/research/topics/life-area-relationships/)

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## Related studies

Cohort study, 2024

Is PMS before pregnancy linked to postpartum depression?

Systematic review, 2022

Does having PMDD increase the risk of depression during pregnancy or after birth?

Case-control study, 2013

Are stress hormones different in women with PMDD?

Survey study, 2023

Could treatments that affect the brain's GABA system help PMDD?

Cohort study, 2001

Do women with PMDD handle stress hormones differently than women without it?

Survey study, 2001

Do women with PMDD have other mental health conditions or personality traits?

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