---
title: Does Vitex agnus castus help PMS, and what causes PMS? | Niyora
description: Risk factors for PMS include delayed menarche (2.5 times increased risk) and painful periods (2.1 times increased risk). Treatment with Vitex agnus castus ext
url: https://niyora.com/research/papers/risk-factors-and-treatment-for-premenstrual-tension-syndrome-2024/
---

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- Does Vitex agnus castus help PMS, and what causes PMS?

Survey study, 2024

# Does Vitex agnus castus help PMS, and what causes PMS?

Risk factors for PMS include delayed menarche (2.5 times increased risk) and painful periods (2.1 times increased risk). Treatment with Vitex agnus castus extract showed 2.8 times higher symptom remission than no treatment.

 Early or limited evidence

824 women

## What they did

Survey of 824 women about PMS, its risk factors, and treatment with Vitex agnus castus Ze 440 fruit extract. Compared symptom remission in treated versus untreated women.

## What they found

Risk factors identified: long period for menstrual development increased PMS risk 2.5 times, and painful menstruation increased risk 2.1 times. Women treated with Vitex agnus castus Ze 440 had 2.8 times higher symptom remission (95% CI 1.23-4.47) compared to untreated women.

## What it means for you

Delayed puberty and painful periods may increase PMS risk. Vitex may help reduce PMS symptoms, though this is observational data without a control group, so cause and effect cannot be proven.

2.5x

Risk increase from delayed menarche

2.1x

Risk increase from painful periods

2.8x

Higher symptom remission with Vitex

## About the study

Original title Risk Factors and Treatment for Premenstrual Tension Syndrome Authors Л. В. Гутикова, Ю.В. Кухарчик, М.А. Павловская Journal Репродуктивное здоровье Восточная Европа Year 2024 Study design Survey study Participants 824 What was tested Vitex agnus castus Ze 440 fruit extract for PMS Open access Yes Read the paper [doi.org/10.34883/pi.2024.14.1.002](https://doi.org/10.34883/pi.2024.14.1.002)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Vitex agnus-castus (chasteberry)](https://niyora.com/research/topics/treatment-vitex/)

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Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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