---
title: Does Dioscorea esculenta powder reduce menstrual pain and PMS symptoms?
description: Yes. Women who took this plant powder for 4 weeks had reduced pain and PMS symptoms, but the sample was extremely small.
url: https://niyora.com/research/papers/the-effect-of-dioscorea-esculenta-powder-on-prostaglandin-e-2-and-cytochrome-c-2024/
---

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- Does Dioscorea esculenta powder reduce menstrual pain and PMS symptoms?

Randomised trial, 2024

# Does Dioscorea esculenta powder reduce menstrual pain and PMS symptoms?

Yes. Women who took this plant powder for 4 weeks had reduced pain and PMS symptoms, but the sample was extremely small.

 Early or limited evidence

10 healthy young women

## What they did

A 4-week crossover trial with 10 young women who received either 300 mg of Dioscorea esculenta powder daily or placebo, then switched treatments after a 4-week break. Blood samples measured inflammation chemicals.

## What they found

After taking Dioscorea esculenta, women had lower levels of two inflammation chemicals and reported less menstrual pain and PMS symptoms compared to placebo.

## What it means for you

This plant powder might reduce period pain and PMS by lowering inflammation. However, only 10 women were studied, so much larger studies are needed to confirm whether this reliably works.

10

Young women studied

300 mg/day

Daily powder dose

4 weeks

Treatment period

## About the study

Original title The effect of Dioscorea esculenta powder on prostaglandin E 2 and cytochrome c oxidase subunit 2 levels, menstrual pain, and premenstrual syndrome in young women: A randomized double-blind controlled trial Authors Sato K, Seto K Journal Nutrition and health Year 2024 Study design Randomised trial Participants 2 What was tested 300 mg per day of Dioscorea esculenta powder for 4 weeks Open access Yes Read the paper [doi.org/10.1177/02601060221130889](https://doi.org/10.1177/02601060221130889)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/)

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