--- title: Does menstrual cycle phase affect anxiety and complications during tooth extraction surgery? description: Yes. Women had significantly higher anxiety and more complications during the secretory phase (second half) of their cycle compared to other phases. Women als url: https://niyora.com/research/papers/the-effect-of-gender-and-menstrual-cycle-phase-on-patents-undergong-mpacted-thrd-2024/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does menstrual cycle phase affect anxiety and complications during tooth extraction surgery? Cohort study, 2024 # Does menstrual cycle phase affect anxiety and complications during tooth extraction surgery? Yes. Women had significantly higher anxiety and more complications during the secretory phase (second half) of their cycle compared to other phases. Women also had higher anxiety than men overall. Early or limited evidence 128 patients (79 women, 49 men) aged 27 years on average, undergoing wisdom tooth extraction ## What they did Prospective study of 128 patients (79 women, 49 men) undergoing impacted third molar extraction. Women's menstrual cycles ranged from 26 to 32 days. Measured preoperative anxiety using three questionnaires. Measured postoperative satisfaction and complications. ## What they found Women had significantly higher anxiety scores than men (STAI-S 94 vs 53, MDAS 16 vs 9, DFS 58 vs 27, all p<0.001). Women had higher complication rates (116 vs 51) and lower satisfaction (40 vs 13) than men (p<0.001). In women, anxiety scores were high during the secretory phase (p<0.001). Complications were high and satisfaction was low during the secretory phase (p<0.001). ## What it means for you Menstrual cycle phase affects how women tolerate oral surgery, with the secretory phase (when hormone levels are high) being the most difficult. Timing surgery earlier in the cycle might reduce anxiety and complications. This is a small study from one clinic about one type of surgery, so findings may not generalize. 79 women, 49 men Study participants 94 vs 53 Anxiety scores: women vs men 27±4.6 years Mean age ## About the study Original title The effect of gender and menstrual cycle phase on patıents undergoıng ımpacted thırd molar surgery: a cross-sectıonal study Authors Geçkil N Journal Medicina oral, patologia oral y cirugia bucal Year 2024 Study design Cohort study Participants 128 What was tested None (comparing different menstrual cycle phases) Open access Yes Read the paper [doi.org/10.4317/medoral.26443](https://doi.org/10.4317/medoral.26443) Original abstract Background: Achieving the best outcomes in surgical procedures requires optimizing all patient-related psychological and physiological factors. This study was carried out to evaluate the preoperative anxiety and fear levels, and postoperative symptoms in patients undergoing impacted third molar surgery, and to compare the relevant psychological and physical findings between genders and between women in different menstrual cycle phases. Material and methods: The population of this prospective and clinical study consisted of patients who applied to faculty of dentistry for the extraction of impacted third molars. The menstrual cycles of the female patients included in the study ranged from 26 to 32 days. The female patients included in the study were divided into three groups according to the first day of the menstrual cycle and bleeding status. All patients were administered Spielberger State-Trait Anxiety Inventory Short Version (STAI-S), Dental Fear Survey (DFS), Modified Dental Anxiety Scale (MDAS) preoperatively, and postoperative satisfaction and complication questionnaires. Results: The mean age of the 128 patients included in the study was 27.04±4.62 years. Of these patients, 79 (61.7%) were female and 49 (38.3%) were male. Female patients had significantly higher STAI-S, MDAS and DFS scores than male patients (94 vs. 53; 16 vs. 9; 58 vs. 27; p<0.001, respectively). In parallel, female patients had significantly higher complication rates, thus significantly lower satisfaction levels than male patients (116 vs. 51; 40 vs. 13; p<0.001, respectively). STAI-S, MDAS and DFS scores were high in women during the secretory phase (p<0.001). In the secretory phase, complications were high and satisfaction was low (p<0.001). Conclusions: The findings of the study reveal that women have a harder time getting through the operation process and that timing is important in reducing preoperative anxiety and fear levels and increasing postoperative satisfaction levels and complication rates. Reproduced under CC-BY. ## Topics [Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2026 Does aerobic or resistance exercise reduce anxiety in women with PMS? Cohort study, 2025 How common is PMS in Chinese teenage girls, and what factors are linked to it? Randomised trial, 2024 Does curcumin reduce depression, anxiety, and stress in women with PMS and dysmenorrhea? Systematic review, 2022 Do mental health disorders get worse during the menstrual cycle? Systematic review, 2021 Does damask rose help reduce menstrual pain, headache, fatigue, anxiety, and bloating? Randomised trial, 2017 Does the combined oral contraceptive pill affect mood? 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