---
title: Does an iron supplement with vitamin C help women with severe iron deficiency?
description: Yes. Hemoglobin increased from 7.577 gm/dl to 11.022 gm/dl and protein increased from 10.056 mg/ml to 27.138 mg/ml over 90 days of treatment.
url: https://niyora.com/research/papers/the-effectiveness-and-protection-of-verbal-ferruginous-ascorbate-in-premenstrual-2021/
---

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- Does an iron supplement with vitamin C help women with severe iron deficiency?

Study, 2021

# Does an iron supplement with vitamin C help women with severe iron deficiency?

Yes. Hemoglobin increased from 7.577 gm/dl to 11.022 gm/dl and protein increased from 10.056 mg/ml to 27.138 mg/ml over 90 days of treatment.

 Early or limited evidence

50 premenstrual women with severe iron deficiency

## What they did

50 premenstrual women with severe iron deficiency were given iron with vitamin C in tablet form three times daily for 90 days. Hemoglobin and protein levels were measured at baseline and after 1, 2, and 3 months.

## What they found

Hemoglobin increased from 7.577 gm/dl to 11.022 gm/dl. Protein level increased from 10.056 mg/ml to 27.138 mg/ml. Common side effects included dark discoloration of stool in 54% of women, nausea in 6%, decreased appetite in 2%, and diarrhea in 2%.

## What it means for you

Iron supplementation with vitamin C effectively increased hemoglobin and protein levels in women with severe iron deficiency. This study treated a blood condition rather than premenstrual syndrome symptoms directly. The main limitation is that there was no untreated comparison group to confirm the improvements came from the treatment.

50

Women treated

90

Days of treatment

54%

Dark stools (side effect)

## About the study

Original title THE EFFECTIVENESS AND PROTECTION OF VERBAL FERRUGINOUS ASCORBATE IN PREMENSTRUAL FEMALES WITH EXTREME IRON INSUFFICIENCY ETIOLATED Authors Muhammad Talal Journal Zenodo (CERN European Organization for Nuclear Research) Year 2021 Study design Study Participants 50 What was tested Iron with vitamin C supplement, one tablet three times daily for 90 days Open access Yes Read the paper [doi.org/10.5281/zenodo.4434209](https://doi.org/10.5281/zenodo.4434209)

## Topics

[Zinc and iron](https://niyora.com/research/topics/treatment-zinc-iron/)

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