---
title: Does Femal help with sleep problems and PMS symptoms? | Niyora
description: Yes. Femal significantly reduced premenstrual sleep disturbances. In women whose main symptom was irritability, Femal also reduced overall PMS symptoms.
url: https://niyora.com/research/papers/the-efficacy-of-femal-in-women-with-premenstrual-syndrome-a-randomised-double-2008/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Does Femal help with sleep problems and PMS symptoms?

Randomised trial, 2008

# Does Femal help with sleep problems and PMS symptoms?

Yes. Femal significantly reduced premenstrual sleep disturbances. In women whose main symptom was irritability, Femal also reduced overall PMS symptoms.

 Moderate study design

101 women with PMS (50 given Femal, 51 given placebo)

## What they did

Randomized controlled trial where 50 women took Femal 160 mg twice daily and 51 took placebo for 4 menstrual cycles. Researchers measured sleep disturbances and overall PMS symptoms.

## What they found

Femal significantly reduced premenstrual sleep disturbances compared to placebo. In a subgroup of women with irritability as their main symptom cluster, Femal also significantly reduced their overall PMS symptom scores. No serious adverse events were reported.

## What it means for you

Femal, a pollen-based herbal product, appears to help with sleep problems before the period. It may help overall PMS symptoms in women whose main complaint is irritability. The benefit for overall symptoms was not seen in women whose main symptom was depression.

101

women studied

160 mg

Femal dose (twice daily)

4

menstrual cycles of treatment

## About the study

Original title The efficacy of Femal in women with premenstrual syndrome: a randomised, double-blind, parallel-group, placebo-controlled, multicentre study Authors Gerhardsen G, Hansen AV, Killi M et al. Journal Advances in therapy Year 2008 Study design Randomised trial Participants 51 What was tested Femal 160 mg taken twice daily for 4 menstrual cycles Read the paper [doi.org/10.1007/s12325-008-0072-4](https://doi.org/10.1007/s12325-008-0072-4)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Irritability and anger](https://niyora.com/research/topics/symptom-irritability-anger/)[Sleep and insomnia](https://niyora.com/research/topics/symptom-sleep/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Randomised trial, 2012

Does Vitex agnus castus work for PMS, and what dose is best?

Randomised trial, 2010

Does Vitex agnus castus (chasteberry) reduce PMS symptoms in Chinese women?

Randomised trial, 2001

Does agnus castus (Vitex) fruit extract reduce premenstrual syndrome symptoms?

Survey study, 2025

Can a chatbot help monitor PMS symptoms over time?

Review, 2023

Can herbs and supplements help with PMS symptoms?

Non-randomised trial, 2021

Does a combination of exercise, ginger milk, and massage help premenstrual syndrome?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗
